健骨口服液质量标准研究  

Quality Control of Jiangu Liquid

作　　者：陆萍[1] 倪东杰[1] 郭良君[1] 谭兴起 郑巍[1] 

机构地区：[1]解放军98医院,浙江湖州313000 [2]解放军85医院,上海200052

出　　处：《解放军药学学报》2014年第4期348-351,共4页Pharmaceutical Journal of Chinese People's Liberation Army

摘　　要：目的建立健骨口服液的质量控制方法。方法采用TLC法对健骨口服液中淫羊藿、黄芪、补骨脂进行定性鉴别;用HPLC法测定口服液中淫羊藿苷的含量。结果薄层色谱中斑点清晰,易于识别;HPLC法精密度、重复性良好。淫羊藿苷对照品在42.0-210.0μg·ml-1,r=0.9993范围内呈良好的线性关系,平均加样回收率为98.15%,RSD为1.18%。结论本法可有效地控制健骨口服液的质量。Objective To establish a quality standard forJianguliquid. Methods TLC was used for identification of radix astragali and psoralea fruits while HPLC was used for quantitative determination of icariin. Results The picture of Epimedii Folium TLC was clear and negative control had no interference. The sample of chlorogenic acid showed a good linear relationship（ r = 0. 9993） in the range of 42. 0- 210. 0 μg·ml- 1. The average recovery was 98. 15%,RSD 1. 18%. Conclusion This method can be used for quality control of Jiangu liquid.

关 键 词：健骨口服液 淫羊藿苷 HPLC 

分 类 号：R927[医药卫生—药学]