68125例育龄期女性丙型肝炎病毒感染状况及流行特征分析  

Prevalence and epidemic characteristics of hepatitis C virus infection among 68125 women of childbearing age

作　　者：宋晓妍[1] 杜红梅[1] 杨丽珍[1] 孟祥颖[1] 贾莉婷[1] 张展[1] 

机构地区：[1]郑州大学第三附属医院检验科,河南郑州450052

出　　处：《中国卫生检验杂志》2014年第16期2377-2379,共3页Chinese Journal of Health Laboratory Technology

摘　　要：目的了解现阶段不同年龄阶段育龄期女性人群丙型肝炎病毒感染状况及流行特征。方法采用酶联免疫吸附试验（ELISA）检测本院2012年1月-2013年10月间68125例育龄期女性丙型肝炎病毒感染状况。结果共筛查出抗-HCV抗体阳性者198例，阳性率为0．29％，16岁～19岁组、20岁～24岁组、25岁-29岁组、30岁～34岁组、35岁～39岁组、40岁-44岁组及45岁-49岁组阳性率分别为0．14％、0．15％、0．12％、0．21％、0．52％、0．71％和1．54％，不同年龄段育龄期女性抗-HCV抗体阳性率比较，差异有统计学意义（X2=211．4，P〈0．001）。城市与农村人群及门诊与住院人群相比阳性率差异均无统计学意义（P〉0．05）。结论与男性及其他年龄阶段的女性人群相比，育龄期女性丙型肝炎病毒感染率呈现较低水平，不同年龄阶段的育龄期女性感染率亦存在差异。Objective To investigate the prevalence and epidemic characteristics of hepatitis C virus infection in women of child bearing age. Methods A total of 68 125 women of ehildrenbearing age were selected to detect the hepatitis C virus infection by enzyme - linked immunosorbent assay （ELISA） from January 2012 to October 2013. Results One hundred and ninety - eight cases were found hepatitis C virus antibody positive. The prevalence of anti - HCV in the whole population was 0. 29%, while the positive rates of anti - HCV in women at age of 16 - 19, 20 ~ 24, 25 ~ 29, 30 ~ 34, 35 - 39, 40 ~ 44 and 45 ~ 49 were 0.14% , 0.15% , 0.12% , 0.21% , 0.52% , 0.71% and 1.54% respectively, and the difference showed statistical signifi- cance among these groups（x2 =211.4, P 〈 0. 001 ）. There were no significant differences in the prevalence rates neither be- tween rural and urban population, nor outpatients and inpatients （ P 〉 0.05 ）. Conclusion Compared to male population and females not at childbearing age, this study showed lower level of HCV prevalence and various prevalence at different age stages in women of childbearing age.

关 键 词：丙型肝炎病毒 育龄期女性 血清流行病学 患病率 

分 类 号：R512.63[医药卫生—内科学]