儿童呼吸道分离的肺炎链球菌耐药性分析  

Analysis of antibiotics resistance for Streptococcus pneumoniae isolated from children's respiratory tract

作　　者：胡利春[1] 傅雅浓 吕火烊[2] 

机构地区：[1]慈溪市妇幼保健院检验科,浙江慈溪315300 [2]浙江省人民医院检验中心,浙江杭州310014

出　　处：《中国卫生检验杂志》2014年第17期2570-2571,共2页Chinese Journal of Health Laboratory Technology

摘　　要：目的调查儿童呼吸道感染肺炎链球菌对常用抗生素的耐药情况。方法采用ATB细菌鉴定仪及API 20STREP鉴定卡进行细菌学鉴定,用E-test试条检测青霉素G、头孢噻肟和万古霉素的MIC,其他药物的药敏试验采用K-B法。结果 53例肺炎链球菌中,青霉素耐药(MIC≥8μg/ml)的肺炎链球菌占20.7%;红霉素、四环素、复方新诺明和克林霉素的耐药率分别为84.9%,75.4%,73.6%,41.5%;万古霉素、头孢噻肟和利福平的耐药率为0。结论本地区儿童呼吸道分离的肺炎链球菌对常用的抗菌药物有较高的耐药性,应当加强儿童呼吸道苛养菌的分离和耐药性监测,合理使用抗生素,减少耐药菌株的产生。Objective To investigate the resistance of Streptococcus pneumoniae isolated from children＇s respiratory tract to com- monly used antibiotics. Methods The bacteriology identification were done by ATB bacterium identifying apparatus and API 20 STREP identification card, with E -test method to detect the Antimicrobial Susceptibility for penicillin G, cefotaxime, vanco- mycin, and the others were tested by the K - B method. Results 53 strains of Streptococcus pneumoniae, the resistant rate of penicillin （ MIC^8 I^g/ml） was 20.7%, erythromycin, tetracycline, cotrimoxazole anc~ clindamycin wererespectively 84.9%, 75.4%, 73.6%, 41.5%, Vancomycin, cefotaxime and rifampicin＇s resistant rate is zero. Conclusion The Streptococcus pneumoniae isolated from the region~ childhood respiratory tract to commonly used antimicrobial agents have higher resistance. We should strengthen the monitoring to the separation of the fastidous bacteria and drug resistance in childhood respiratory tract, rationally use of antibiotics, and, reduce the generation of drug - resistant strains.

关 键 词：儿童 呼吸道 肺炎链球菌 耐药性 

分 类 号：R378.993[医药卫生—病原生物学]