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作 者:李静伟[1] 潘定权[1] 何康宏[1] 史晓林[2]
机构地区:[1]浙江中医药大学,杭州310053 [2]浙江中医药大学附属第二医院,杭州310005
出 处:《中国骨质疏松杂志》2014年第8期920-923,共4页Chinese Journal of Osteoporosis
基 金:2013年国家中医药行业科研专项(201307010)
摘 要:目的探讨改良五禽戏防治原发Ⅰ型骨质疏松症的临床疗效。方法将60例原发Ⅰ型骨质疏松症患者随机分成2组,试验组30例予华佗五禽戏锻炼,对照组30例保持日常生活不变,于试验前、试验后6个月对2组腰椎骨密度值、骨代谢指标(I型原胶原N端前肽和I型胶原羧基末端肽)、腰背部疼痛评分(VAS评分)的变化情况进行统计分析。结果试验6个月后,试验组腰椎骨密度较对照组无统计学意义(P>0.05),但骨代谢指标、腰背部疼痛评分(VAS评分)较对照组显著降低(P<0.05)。结论改良五禽戏锻炼在短期内提高腰椎BMD的作用不甚明显,但可显著降低原发Ⅰ型骨质疏松患者血清中PINP、S-CTX水平、腰背部疼痛评分,改善患者生活质量,是防治骨质疏松症的一种有效方法。Objective To investigate the clinical effect of modified five-bird game in the prevention and treatment of primary type I osteoporosis. Methods Sixty patients with primary type I osteoporosis were randomly divided into 2 groups. Thirty patients in experimental group exercised five-bird game,while the other 30 patients in the control group remained unchanged in daily life. The bone mineral density( BMD) of the lumbar vertebrae was detected before the experiment and 6 months after the experiment. The bone metabolism indexes,including procollagen I N-terminal propeptide and serum cosslaps telopeptides of type I collagen,were also detected. VAS of low back pain was recorded. The changes of BMD,bone metabolism indexes,and VAS were statistically analyzed. Results After 6-month experiment,BMD of the lumbar vertebrae in experimental group showed no statistical significance compared with that in control group( P 〉 0. 05). But the bone metabolism indexs and VAS score of the low back pain in experimental group decreased significantly compared with those in control group( P 〈 0. 05). Conclusion Modified five-bird game exercise has little effect on improving BMD of the lumbar vertebrae in a short term,but it can significantly reduce serum PINP and S-CTX levels and VAS score of the low back pain in patients with primary type I osteoporosis and improve the quality of patients’ life. So,it is an effective method for the prevention and treatment of osteoporosis.
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