哮喘患者血常规、血清总IgE及支气管激发试验分析  

作　　者：赵素娥[1] 彭毅强[2] 

机构地区：[1]中南大学湘雅三医院,湖南410013 [2]长沙市中心医院,410004

出　　处：《当代医学》2014年第27期1-2,共2页Contemporary Medicine

摘　　要：目的了解不同类型哮喘患者的气道反应性。方法按血常规将65例哮喘患者分为血嗜酸性粒细胞增高组A组和血嗜酸性粒细胞无增高组B组,对不同组血清总IgE、气道阻力及激发剂量进行对比分析。结果血嗜酸性粒细胞增高组19例,其中血清总IgE增高15例(78.95%),气道阻力增高16例(84.21%);血嗜酸性粒细胞无增高组46例中,分别为21例(45.65%)与27例(58.70%),2组差异均具有统计学意义(P<0.05)。2组激发剂量分别为(1.15±0.75)mg和(1.67±0.69)mg,差异具有显著统计学意义(P<0.05)。结论血嗜酸性粒细胞增高哮喘多为IgE介导的哮喘,此类哮喘较血嗜酸性粒细胞无增高哮喘气道阻力高,气道反应性亦高。Objective To study the airway reactivity in patients with different kinds of asthma.Methods According to blood routine,65 asthma patients were divided into increased eosinophilia percentage group and unincreased eosinophils percentage group.Total IgE concentration,airway resistance and provocative dose in the two groups were comparatively analyzed.Results Among 19 asthma patients with increased eosinophilia percentage ,the total serum IgE increased increased（78.95%）, airway resistance increased in 16 cases （84.21%）; The other 46 cases were 21 cases（45.65%） and 27 cases （58.70%） respectively. Difference between the two groups were statistically significant.Conclusion Asthma with increased eosinophilia percentage are mainly mediated by IgE, and airway resistance as well as airwayreactivity is higher than those of asthma patients with unincreased eosinophils percentage.

关 键 词：支气管哮喘 血常规 免疫球蛋白E 支气管激发试验 

分 类 号：R562.25[医药卫生—呼吸系统]