子宫动脉栓塞化疗治疗特殊部位妊娠  

Uterine artery chemotherapy and embolization in the treatment of special site pregnancy

作　　者：桂定清 刘芳[1] 张力忆[1] 余晓梅[1] 符伟[1] 戚瑞虹 

机构地区：[1]达州市中心医院妇产科,四川省达州635000

出　　处：《中国基层医药》2014年第20期3134-3136,共3页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的：探讨子宫动脉栓塞化疗治疗特殊部位妊娠的临床效果。方法选取36例特殊部位妊娠患者作为研究对象，将其根据随机数字表法均分为观察组和对照组。对照组采用子宫动脉介入栓塞后清宫治疗，观察组采用双侧子宫动脉灌注甲氨喋呤联合栓塞后清宫治疗，比较两组β-HCG水平恢复正常所需时间、术中出血量、住院时间及并发症发生率。结果治疗后观察组β-HCG水平恢复正常所需时间为（27．3±3．2）h，术中出血量为（120．5±18．3）mL，住院时间为（85．6±8．4）h；对照组分别为（76．4±8．2）h、（375．16±8．4）mL及（147．1±10．5）h，观察组β-HCG水平恢复正常所需时间及住院时间短于对照组，术中出血量少于对照组（ t＝6．75、4．54、4．43，均P＜0．05）；观察组并发症发生率为16．8％，对照组为50．1％，两组并发症发生率差异有统计学意义（χ2＝4．49，P＜0．05）。结论采用子宫动脉栓塞化疗治疗特殊部位妊娠能显著缩短患者住院时间及β-HCG水平恢复正常所需时间，减少术中出血量，临床效果好，可作为治疗特殊部位妊娠的有效方法。Objective To investigate the clinical effect of uterine artery embolization chemotherapy in the treatment of special site pregnancy .Methods 36 patients with special site pregnacy were randomly divided into the observation group and control group .The control group received uterine curettage after uterine artery embolization treatment,the observation group received bilateral uterine artery perfusion of methotrexate combined with uterine cu -rettage after embolization therapy .Time of-HCG returned to normal ,intraoperative blood loss ,hospitalization time and incidence rate of complications were compared between the two groups .Results After treatment,the time of -HCG returned to normal,intraoperative blood loss and hospitalization time in the observation group were （27.3 ±3.2）h, （120.5 ±18.3） mL,（85.6 ±8.4） h,which were significantly less than （76.4 ±8.2） h,（375.1 ±68.4） ml and （147.1 ±10.5）h in the control group （t=6.75,4.54,4.43,all P〈0.05）.The incidence rate of complication in the observation group was 16.8%,which was significantly lower than 50.1% in the control group （χ2 =4.49,P 〈0.05）.Conclusion The uterine artery chemotherapy and embolization in the treatment of special parts of pregnancy can significantly shorten the hospitalization time and time of -HCG returned to normal ,reduce the intraoperative blood loss,the clinical effect is good ,it can be used as an effective method for the treatment of special site pregnancy .

关 键 词：妊娠 异位 栓塞 治疗性 化疗治疗 

分 类 号：R714.22[医药卫生—妇产科学]