胆酸1,2,3-三氮唑衍生物的合成与表征  

Synthesis and Characterization of Bile Acid 1,2,3-three Nitrogen Triazole Derivatives

作　　者：翟亮亮[1,2] 陈瑨[2] 霍萃萌[2] 代本才[2] 赵永德[2] 

机构地区：[1]河南大学化学化工学院,河南开封475001 [2]河南省科学院化学研究所有限公司,郑州450002

出　　处：《河南科学》2014年第8期1399-1403,共5页Henan Science

摘　　要：以胆酸为起始原料,依次经过酯化反应、3位羟基叠氮化反应、点击反应合成出8个含有4-芳基-1,2,3-三唑环的胆酸衍生物,所有化合物均未见文献报道.所得到的化合物结构均经过IR,1H NMR,13C NMR,ESI-MS,熔点测定等手段的确认.With bile acid as starting material,eight bile acid derivatives containing 4-aryl-1,2,3-triazole ring were synthesized by esterification,3-OH azide reaction,click reaction. The structures of these compands were characterized by IR,NMR,MS spectra and melting point determination method,and all the compands were confirmed.

关 键 词：1 2 3-三唑 胆酸 点击反应 

分 类 号：O62[理学—有机化学]