替加环素对鲍曼不动杆菌作用研究的文献计量分析  

Literature measurement analysis of tigecycline against Acinetobacter baumannii role in research

作　　者：白艳[1] 王瑾[2] 谷彩梅 刘斌[2] 曹江[2] 梅和坤[2] 江学维[2] 牛卉[2] 王睿[2] 

机构地区：[1]中国人民解放军总医院药品保障中心,北京100853 [2]中国人民解放军总医院药物临床研究中心,北京100853 [3]大理学院药学与化学学院,云南大理671000

出　　处：《中国临床药理学杂志》2014年第9期825-827,共3页The Chinese Journal of Clinical Pharmacology

基　　金：十二五国家重大科技专项基金资助项目(2012ZX09303004-002)

摘　　要：目的了解国内外替加环素作用于鲍曼不动杆菌的研究动态及热点内容。方法检索从建库至2014-03的Pubmed、Embase、Web of Science及CNKI数据库中替加环素对鲍曼不动杆菌作用相关文献;用Endnote7.0软件进行分类整理分析。结果纳入英文文献227篇,中文文献34篇;发表的文献类型以论著为主;文献的主要内容为替加环素对鲍曼不动杆菌作用相关的体外基础研究、动物实验、病例分析等;研究内容主要涉及耐药机制、体外药敏实验及联合用药等。结论替加环素作用于鲍曼不动杆菌的研究受到广泛关注,尤其是鲍曼不动杆菌对替加环素耐药机制的研究愈加深入。Objective To analyze researches and hot issuses on tigecycline against Acinetobacter baumannii around the world. Methods Literatures were searched in Pubmed,Embase,Web of Science,and CNKI from the beginning to March,2014. Endnote7. 0 was used to sort out and summarize. Results A total of 227 English articles and 34 Chinese articles were collected and the majority was characterized asoriginal article.Those articles were focused on the basic research of tigecycline against Acinetobacter baumannii in vitro,animal experiments and case analysis.Resistance mechanism,drug susceptibility test in vitro,and drug combination were frequently involved. Conclusion The study on tigecycline against Acinetobacter baumannii increasingly has attracted global concern,especially the study on resistance mechanisms to tigecycline has gone further.

关 键 词：替加环素 鲍曼不动杆菌 文献计量分析 

分 类 号：R969.3[医药卫生—药理学] R978.1[医药卫生—药学]