化瘀解毒组方治疗子宫内膜异位症58例疗效观察  

Clinical Observation on Stasis-Transforming Toxin-Resolving Formula for 58 Cases of Endometriosis

作　　者：孙帅[1] 沈慰[1] 翟东霞[1] 张丹英[1] 王针织[1] 白玲玲[1] 单清菁[1] 刘益群[1] 俞超芹[1] 

机构地区：[1]第二军医大学附属长海医院,上海市杨浦区长海路168号200433

出　　处：《中医杂志》2014年第19期1668-1671,共4页Journal of Traditional Chinese Medicine

摘　　要：目的观察化瘀解毒组方治疗子宫内膜异位症(EMT)患者的临床疗效。方法采用患者自身治疗前后对比的方法,58例EMT患者均给予化瘀解毒方口服,每日1剂,分早晚2次口服,同时睡前先将热敷方敷于小腹或患处30min,然后用冷敷方敷于同一位置3h,月经期停用冷敷,并继续口服化瘀解毒方及热敷治疗,治疗3个月后评价临床疗效。比较患者治疗前后的痛经及盆腔痛评分、中医症状评分、卵巢内膜样囊肿大小、血清CA125水平,并观察不良反应。结果临床疗效总有效率为82.8%。患者治疗前后痛经及盆腔痛评分均明显降低(P<0.01);患者治疗前后除月经量外,其他中医症状评分均明显降低(P<0.01);治疗后卵巢内膜样囊肿明显缩小(P<0.05);血清CA125升高患者治疗前后比较差异无统计学意义(P>0.05)。治疗期间未发现患者出现明显的副作用。结论化瘀解毒组方能够减轻EMT患者的痛经及盆腔痛,明显改善中医相关症状,且无明显不良反应。Objective To observe the therapeutic effect of Stasis-Transforming Toxin-Resolving Formula（ STTRF） for endometriosis（ EMT）. Methods Totally 58 cases of EMT were given STTRF one dose daily. The hot compress was given before bedtime for 30 min and cold compress was given at the same position for 3 hours. During the menstrual period cold compress was deactivated. The therapeutic effect was evaluated after 3-month treatment.The dysmenorrhea score,pelvic pain score,TCM symptom score,ovarian endometrioid cyst size and serum CA125 level were compared before and after treatment. The adverse reactions were observed. Results The total effective rate was 82. 8%. The dysmenorrhea score and pelvic pain score were decreased after treatment（ P〈0. 01）. The TCM symptom scores were significantly decreased after treatment except the menstrual flow score（ P〈0. 05）. The ovarian endometrioid cyst size was significantly reduced after treatment（ P〈0. 05）. The CA125 level was increased after treatment but with no significant difference between before and after treatment（ P〈0. 05）. There was no obvious adverse reaction during treatment. Conclusion STTRF can relieve dysmenorrhea,pelvic pain and TCM symptoms with no adverse reaction.

关 键 词：化瘀解毒组方 子宫内膜异位症 痛经 中药外敷 

分 类 号：R271.9[医药卫生—中西医结合]