妇炎消胶囊质量标准的研究  

Study on Quality Standards for Fuyanxiao Capsules

作　　者：陈惠玲[1] 曾荣洁[1] 

机构地区：[1]厦门市药品检验所,厦门361012

出　　处：《中国药品标准》2014年第4期272-275,共4页Drug Standards of China

摘　　要：目的：提高完善妇炎消胶囊的质量标准。方法：采用薄层色谱法鉴别败酱草；采用高效液相色谱法测定大黄中大黄素和大黄酚的含量；采用高效液相色谱法测定牡丹皮中芍药苷的含量。结果：大黄素在0.0080～0.2012μg范围内呈良好的线性关系（r＝1.0000），平均回收率为98.1％（RSD＝3.0％，n＝9）；大黄酚在0.0262～0.6550μg范围内呈良好的线性关系（r＝1.0000），平均回收率为102.4％（ RSD＝2.6％，n＝9）；芍药苷在0.0997～1.9937μg范围内呈良好的线性关系（r＝1.0000），平均回收率为103.3％（ RSD＝1.5％，n＝9）。结论：建立的方法准确可靠，适用于妇炎消胶囊的质量控制。Objective：To establish quality standard for Fuyanxiao Capsules.Methods： Herba Patriniae was identified by TLC; the concentration of emodin ,chrysophanol and paeoniflorin were determined by HPLC.Results：The calibration curveof emodin was linear within the range of 0.0080-0.2012 μg（r=1.0000）, the average recovery was 98.1%with RSD of 3.0%（n=9）;the range of chry-sophanol was 0.0262-0.6550 μg（r=1.0000）,the average recovery was 102.4%with RSD at 2.6%（n=9） and that of paeoniflorin was 0.0997-1.9937 μg（r=1.0000）, average recovery was 103.3%and RSD of 1.5%（n=9）.Conclusion：The methods are sen-sitive,accurate and suitable for the quality control of Fuyanxiao Capsules.

关 键 词：妇炎消胶囊 大黄素 大黄酚 芍药苷 败酱草 质量标准 

分 类 号：R921.2[医药卫生—药学]