某企业职业人群消化性溃疡发病风险度分析  

Risk analysis of peptic ulcer in an occupational population

作　　者：周蕾[1] 李娟生[1] 蒲宏全[2] 任晓卫[1] 李海燕[2] 胡晓斌[1] 苏辉[2] 程治远[1] 

机构地区：[1]兰州大学公共卫生学院流行病与卫生统计研究所,甘肃兰州730000 [2]金川集团股份有限公司职工医院,甘肃金昌737100

出　　处：《工业卫生与职业病》2014年第5期327-329,共3页Industrial Health and Occupational Diseases

基　　金：国家医改重大专项;国家重大公共卫生服务专项(财社[2012]-026);金川集团公司与兰州大学合作项目(金科综2012-13)

摘　　要：目的 探讨职业人群中消化性溃疡（PU）发病的危险因素及其风险度,为职业人群PU的预防提供依据。方法 从该企业职业人群中随机抽取9 463例职工,以其中明确诊断为PU的363例职工为病例组,通过成组匹配,选择与病例组均衡可比的400例健康人为对照组,采用同一调查表进行面对面访谈。按年龄分层进行分层分析和交互作用分析。结果 男性、吸烟、接触粉尘、饮酒和干硬饮食是PU发生的独立危险因素（OR=1.411～2.485,P〈0.05）,它们的病因分值分别为0.421、0.318、0.243、0.188、0.093。危险因素两两交互作用分析,男性与吸烟、男性和饮酒、吸烟和干硬饮食、男性和干硬饮食的交互作用指数分别为0.313、0.186、0.063和0.015。结论 男性、吸烟、粉尘暴露、饮酒和干硬饮食是职业人群中PU发病的独立危险因素,两两因素间无明显的协同作用。Objective to explore the role of etiology fraction and interaction of risk factors in the development of peptic ulcer in an occupational population,in order to provide evidence for disease prevention.Methods 9463 workers were sampled randomly from the whole working population in this firm,and 363 diagnosed cases of peptic ulcer and 400 controls were investigated by case-control study.Using self-designed questionnaires,we conducted interviews by face to face interview.After the age stratification,the independent risk factors of peptic ulcer were analyzed.Results the results showed that male,smoking,dust espousing,drinking and preferring hard foods were independent risk factors of peptic ulcer（OR=1.411～2.485,P〈0.05）.EFs of the risk factors were 0.421,0.318,0.243,0.188 and 0.093,respectively.The interaction index of male with smoking,male with drinking,smoking with preferring hard foods and male with preferring hard foods were 0.313,0.186,0.063 and 0.015.Conclusions male,smoking,dust espousing,drinking and preferring hard foods were independent risk factors of peptic ulcer in occupational population.But there is no interaction effect between two risk factors.

关 键 词：职业人群 消化性溃疡 病因分值 交互效应 

分 类 号：R181.2[医药卫生—流行病学]