冠心病血瘀证症状体征的异质性及与遗传的关系  

Study on the relationship between the heterogeneity of blood stasis syndrome and heredity in coronary heart disease

作　　者：王萍[1,2] 杨海燕[1] 王丽萍[2] 袁肇凯[2] 

机构地区：[1]江西中医药大学,南昌330000 [2]湖南中医药大学,长沙410000

出　　处：《中华中医药杂志》2014年第9期2913-2915,共3页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：国家自然科学基金资助项目(No.30973717)~~

摘　　要：目的:研究冠心病血瘀证的症状体征是否存在着异质性的分类现象,及其与遗传的关系。方法:通过系统聚类分析方法对辨证依据的症状体征(量化赋值)进行分析。结果:冠心病血瘀证患者的症状体征共分析了胸闷、刺痛、甲青、舌色等10类要素。聚类分析可分为两类,每类均纳入33例。一类以胸闷、唇青和面紫为主要表现,另一类在上类基础上另有刺痛和舌色改变。且前一类以非家系病例为主,后一类以家系病例为主。结论:纳入的冠心病血瘀证通过症状体征具有异质性特点,且这种分类与遗传有关。Objective： To study the signs and symptoms of blood stasis syndrome in coronary heart disease （CHD）, whether exists the heterogeneous classification phenomenon and its relationship with heredity. Methods： The symptoms and signs of syndrome differentiation （quantified assignment） are analysis by using systemic clustering analysis method. Results： 10 kinds of the clinical symptoms and signs of blood stasis syndrome in patients with coronary heart disease were analysed, such as chest tightness, tingling, Nail cyanosis and tongue color. Cluster analysis can be divided into two categories, each category are included in 33 cases. A kind of category is divided by chest tightness, cyanosis of the lips and face purple as the main performance, another in the class on the basis of the former increase the stinging and tongue color change. And the first class mainly contain the non family cases, but another bring into the family cases. Conclusion： The CHD has heterogeneous characteristics according to the symptoms and signs of blood stasis syndrome, and this classification is related to heredity.

关 键 词：冠心病 血瘀证 症状体征 异质性 遗传 

分 类 号：R259[医药卫生—中西医结合]