聚六亚甲基单胍盐酸盐黏均相对分子质量的测定及抑菌效果  

Determination of Viscosity-average Relative Molecular Weight of Polyhexamethylene Guanidine Hydrochloride and its Antibacterial Effect

作　　者：于洪梅[1] 贾宏敏[1] 朱秀慧[1,2] 陈阳[1] 庞晶[1] 

机构地区：[1]辽宁科技大学化学工程学院,鞍山114051 [2]营口理工学院,营口115014

出　　处：《化学教育》2014年第18期22-25,共4页Chinese Journal of Chemical Education

基　　金：2012年辽宁省鞍山市科技基金项目

摘　　要：采用黏度法测定新型高分子聚合物杀菌消毒剂——聚六亚甲基单胍盐酸盐的平均相对分子质量.聚六亚甲基单胍盐酸盐溶液浓度在0.04 g/mL时,利用文献值K=3.8×10^-3 g/mol、α=1.01,可计算出该自制的聚六亚甲基单胍盐酸盐的平均相对分子质量为2495.在相同的浓度下,不同相对分子质量的聚六亚甲基单胍盐酸盐对大肠杆菌、金黄色葡萄球菌、白色葡萄球菌和铜绿假单胞菌均有一定的抑菌作用,并且抑菌效果均随着相对分子质量的增加而增加.The average relative molecular weight of polyhexamethylene guanidine hydrochloride, which is a novel polymer disinfectant, is determined by the viscosimetry. Using the literature values of K=3.8×10^-3 g/mol and α=1. 01, the average relative molecular weight of the self-made polyhexamethylene guanidine hydrochloride is 2495, when its concentration is 0. 04 g/ mL. The results showed that polyhexamethylene guanidine hydrochloride with different relative molecular weight has certain antibacterial effects on escherichia toll, staphylococcus aureus, staphylococcus and pseudomonas aeruginosa at the same concentrations, and antibacterial effect is increased with the increase of relative molecular weight.

关 键 词：聚六亚甲基单胍盐酸盐 黏度法 相对分子质量 抑菌效果 

分 类 号：O631.61-4[理学—高分子化学] G642[理学—化学]