单腔深静脉管置入引流联合聚桂醇硬化治疗巨大肝肾囊肿安全性及疗效观察  

Lauromacrogol Sclerotherapy and the Drainage by Deep Vein Single Lumen Tube in the Treatment of Large Hepatic or Renal Cysts

作　　者：邹容[1] 狄镇海[1] 张建[1] 毛学群[1] 谭中宝[1] 王庆庆[1] 王美荣[1] 张爱琴[1] 

机构地区：[1]江苏大学附属医院介入放射科,江苏省镇江市212001

出　　处：《中国全科医学》2014年第24期2862-2864,共3页Chinese General Practice

摘　　要：目的探讨单腔深静脉管置入引流联合聚桂醇硬化治疗巨大肝肾囊肿的不良反应及疗效。方法选取2006年1月—2009年12月江苏大学附属医院收治的巨大肝肾囊肿患者31例为对照组,2010年1月—2013年1月收治的巨大肝肾囊肿患者32例为研究组,均置入单腔深静脉管,充分引流后对照组注入无水乙醇、研究组注入聚桂醇进行硬化治疗,观察并记录治疗过程中患者不良反应及术后6个月的治疗效果。结果对照组9例(29.0%)患者出现轻中度腹痛、面红、心悸、头晕、恶心等表现;研究组2例(6.2%)患者出现穿刺部位轻度胀痛不适,无腹痛、无醉酒样反应。两组患者不良反应发生率比较,差异有统计学意义(χ2=5.671,P=0.017)。术后6个月复查B超或CT,研究组25例治愈,7例有效;对照组24例治愈,7例有效。两组治疗效果比较,差异无统计学意义(u=-0.067,P=0.947)。结论单腔深静脉管置入引流联合聚桂醇硬化治疗巨大肝肾囊肿简单、安全、有效,聚桂醇疗效与无水乙醇相当,但不良反应更少,患者对其耐受性更好。Objective To study the therapeutic effects and adverse reactions of drainage by deep vein single lumen tube and lauromacrogol sclerotherapy in the treatment of large hepatic or renal cysts. Methods 31 patients with large hepatic or renal cysts admitted to the Affiliated Hospital of Jiangsu University from January 2006 to December 2009 were selected as control group,while 32 patients with large hepatic or renal cysts admitted from January 2010 to January 2013 were selected as study group. The two groups were both placed with deep vein single lumen tube. After fully drainage,the control group was injected with anhydrous alcohol while the study group was injected with lauromacrogol to have sclerotherapy. The adverse reactions and the ther-apeutic effect after six months were both recorded. Results 9 cases （ 29. 0%）in the control group showed moderate stomach-ache,flushed face,palpitation,dizziness and nausea. 2 cases（6. 2%）in the study group showed mild distending pain in the injection site,but showed no stomachache and drunk-like response. The adverse reaction rate between the two groups showed statistically significant differences（χ2 =5. 671,P=0. 017）. Type-B ultrasound or CT six months after treatment showed that 25 cases were cured and 7 cases were improved in the study group,while 24 cases were cured and 7 cases were improved in the control group. The therapeutic effect between the two groups showed no statistically significant difference（ u = -0. 067,P =0. 947 ） . Conclusion The drainage by deep vein single lumen tube and lauromacrogol sclerotherapy in the treatment of large he-patic or renal cysts is simple,safe and effective. The effect of lauromacrogol and anhydrous alcohol is pretty much the same,but has fewer adverse reactions and better tolerance.

关 键 词：囊肿 穿刺抽液术 聚桂醇 乙醇 

分 类 号：R692[医药卫生—泌尿科学]