慢性HBV感染相关疾病患者的中医体质分布规律研究  

Study on distribution of TCM constitutions of chronic HBV infection-related diseases

作　　者：申弘[1] 凌琪华[2] 杨涛[2] 陈逸云[1] 叶青艳[1] 陈建杰[1,2] 

机构地区：[1]上海中医药大学附属曙光医院肝病科,上海200021 [2]上海中医药大学附属曙光医院传染病研究所(筹),上海201203

出　　处：《上海中医药杂志》2014年第9期12-16,共5页Shanghai Journal of Traditional Chinese Medicine

基　　金：国家中医药管理局重点学科中医传染病学项目(2010);上海市名老中医学术经验研究工作室建设项目(ZYSNXD-CC-MZY003)

摘　　要：目的基于文献调研,总结慢性HBV感染相关疾病患者的中医体质分布规律。方法检索近10年来有关慢性HBV感染相关疾病患者中医体质学研究的文献,采用文献计量学及系统综述的方法,按照制定的标准提取相关的中医体质分布资料,按照疾病类别进行不同体质类型的频数汇总,对不同疾病患者的中医体质分布情况进行分析比较。结果 HBV携带者中,平和质占52.79%,气虚质占8.42%,湿热质占6.94%,阳虚质占6.59%,气郁质占6.12%,其余体质类型占19.15%;慢性乙型肝炎患者中,湿热质占26.68%,气虚质占20.75%,气郁质占11.93%,阴虚质占10.69%,其余体质类型占29.95%;乙型肝炎肝硬化(纤维化)患者者中,阴虚质占33.96%,平和质占29.25%,气虚质占28.30%,其他体质占8.49%;HBV相关的原发性肝癌患者中,平和质占18.92%,阳虚质占17.94%,气虚质占14.74%,瘀血质占13.76%,湿热质占13.02%,其余体质类型占21.62%。结论慢性HBV感染不同相关疾病患者有着特定的中医体质分布规律:HBV携带者中平和质最多见,但有一定的偏颇;慢性乙型肝炎患者主要表现为湿热质、气虚质、气郁质、阴虚质;乙型肝炎肝硬化(纤维化)患者主要表现为阴虚质、气虚质等偏颇体质;HBV相关的原发性肝癌患者主要表现为阳虚质、气虚质、瘀血质、湿热质等偏颇体质。Objective To summary the distribution of TCM constitutions of the chronic HBV infection-related diseases based on literature review. Methods By adopting methods of bibliometrics and systematic review, we search comprehensively the literature on epidemiology investigation of TCM constitutions of the chronic HBV infection-related diseases by computers, and collect the relevant date to compute and analyze their frequency or ratio of constitutions in different categories of disease. Results The ratio of normality in chronic HBV carriers is 52.79% , and Qi-defieiency accounts for 8.42% , dampness-heat accounts for 6.94% , Yangdeficiency accounts for 6.59% , Qi depression accounts for 6.12% , the rest accounts for 19.15%. In patients with chronic hepatitis B, dampness-heat accounts for 26.68% , Qi-deficiency accounts for 20.75% , Qi depression accounts for 11.93%, Yin-deficiency accounts for 10.69%, and the rest accounts for 29.95%. In the patients with advanced fibrosis after chronic hepatitis B, the ratio of Yiu-defieiency is 33.96% , and normality accounts for 29.25% , Qi-deficicncy accounts for 28.30% , the rest accounts for 8.49%. The ratio of normality of patients with HBV-related primary liver cancer accounts for 18.92% , Yang-deficieucy accounts for 17.94% , Qi-deficiency accounts for 14.74% , blood stasis accounts for 13.76% , dampness-heat accounts for 13.02% , the rest accounting for 21.62%. Conclusion Different diseases have specific distribution of TCM constitutions. Normality, accompanied by a few abnormal constitutions, is the most common constitution in chronic HBV carriers. Dampness-heat, Qi-dcficiency, dampness-depression constitution, and Yin-deficiency are exhibited mainly in patients with chronic hepatitis B. Qi-deficiency and Yin-deficieney are main abnormal constitutions of the patients with advanced fibrosis after chronic hepatitis B. Yang-deficiency, Qi-deficiency, blood stasis, and dampness-heat are the major abnormal constitutions of patients with HBV-related primary liver cancer.

关 键 词：乙肝病毒 乙型肝炎 肝纤维化 肝癌 中医体质 分布规律 

分 类 号：R259[医药卫生—中西医结合]