1例头孢曲松钠过敏性休克致持久植物人状态分析  

Ceftriaxone-induced anaphylactic shock resulting in a persistent vegetative state

作　　者：高静[1] 韩佳[1] 惠慧[1] 王来成[1] 

机构地区：[1]徐州医学院附属医院药学部,江苏徐州221006

出　　处：《北方药学》2014年第11期32-33,共2页Journal of North Pharmacy

摘　　要：1例47岁女性患者因急性上呼吸道感染就诊,给予静脉滴注头孢曲松钠2.0g。患者静滴约3min时,出现四肢抽搐、口吐白沫,意识丧失、呼吸微弱。立即停药,予以面罩辅助通气给氧、心电监护,患者此时血压测不出,心率50次/min。给予气管插管接呼吸机辅助通气,抗休克药物应用,心率上升至150次/min。收入院急诊ICU继续抢救治疗。入院后患者一直处于昏迷状态,转入神经内科普通病房。入院后49d患者处于持久植物人状态,时有无意识抓握、眨眼等,对声音刺激有反应,意识状态无明显变化,患者家属要求自动出院。A 47-year-old woman received an intravenous infusion of ceftriaxone sodium 2.0g for her acute upper respiratory infection. About 3 minutes after infusion start, the patient experienced unconsciousness, convulsions,, foam at mouth and dyspnea. The medicine was discontinued immediately. Her blood pressure was undetectable, heart sounds was not heared and heart rate was 50 times/min. After received endotracheal intubation and anti-shock drug, her heart rate rose to 150 times/min. The patient was hospitalized and received further treatment in ICU. In the course of hospitalization, the patient remained in comatose state, then shfited to general ward of department of neurology. On day 49 of admission the patient remained in persistent vegetative state .She had unconscious grasp, blink and responded to sound. There was no significant change of her conscious state . The patient discharged at the request of patient ＇s relatives.

关 键 词：头孢曲松钠 过敏性休克 植物人状态 

分 类 号：R595.5[医药卫生—内科学]