51例药源性过敏性休克药师分析  

51 cases of drug-induced anaphylaxis pharmacist analysis

作　　者：陈梅[1] 王维忠[1] 

机构地区：[1]江苏泰州市人民医院,泰州225300

出　　处：《北方药学》2014年第11期146-148,共3页Journal of North Pharmacy

摘　　要：目的:了解我院药源性过敏性休克发生的情况和特点,分析药源性过敏性休克发生的可能因素,为医院安全、合理用药提供参考信息。方法:对我院51例过敏性休克不良反应报告以及过敏性休克住院患者病历进行回顾性统计和分析。结果:发生过敏性休克患者年龄、性别没有显著差异;涉及药物以抗菌药物为主,其中又以β-内酰胺类和氟喹诺酮类为主;涉及静脉、肌内、口服和外用四种给药方式,以静脉给药为主;患者临床表现都以血压的变化合并皮肤及其黏膜系统、呼吸系统、神经系统、心血管系统、消化系统的表现为主。结论:加强药源性过敏性休克的报告与监测工作,及时分析相关信息可以提高医院安全用药风险能力,提高医院药物警戒工作水平。Objective： To understand the situation and feature of drug-induced anaphylactic shock of our hospital and analyze the possible factors of the occurrence of drug-induced anaphylaxis in order to provide reference information.Method： Retrospective statistic and analyze 51 reports of untoward effect and medical charts of inpatients for anaphylaetic shock.Result： There is no significant discrepancy of age and sex for anaphylactic shock patients; the main drug is antibiotics, especiallyl3-1actam and quinolones; the related drugging methods are intravenous administration, intramuscular medication oral administration and topical, intravenous administration is the main method; clinical manifestation of patient is mainly variation of blood pressure as well as mueosal system, respiratory system, nervous system, cardiovascular system, digestive system.Conclusion： Enhance the reporting and monitoring task of anaphylactie shock, analyze the related information in order to improve the capacity of safety applicationof drugs for hospital, improve medicine warning level for hospital.

关 键 词：药品不良反应 药源性疾病 过敏性休克 

分 类 号：R595.3[医药卫生—内科学]