小剂量阿司匹林致不良反应的文献分析及护理  

Literature analysis on adverse reactions induced by low-dose aspirin and nursing care of it

作　　者：田敏[1] 郎宗娥[2] 李雪梅[1] 

机构地区：[1]中国人民解放军第三军医大学第二附属医院 [2]重庆市涪陵中心医院

出　　处：《全科护理》2014年第24期2209-2212,共4页Chinese General Practice Nursing

摘　　要：[目的]了解小剂量阿司匹林(75mg/d^150mg/d)致不良反应发生的特点、趋势及相关因素。[方法]检索《中国期刊全文数据库》2000年—2013年收载的有关小剂量阿司匹林致不良反应文献,筛选出符合卫生部不良反应诊断标准的文献27篇,共125例不良反应病例,并进行分类、统计、分析。[结果]小剂量阿司匹林不良反应以消化系统、血液系统的损害例数较多,占总例数的80.0%和5.6%。消化系统损害以上消化道出血为主,血液系统损害以血小板减少为主要表现。[结论]临床上小剂量使用阿司匹林过程中可能出现药物不良反应,应加强病人用药教育,密切关注不良反应,及时调整给药方法,以确保用药安全。Obj ective：To probe into the characteristics,tendency and related factors of adverse drug reactions （ADR）induced by low dose aspirin.Methods：A total of 27 literatures on adverse reactions induced by low dose aspirin according with ADR diagnosis standard were retrieved from CNKI from 2000 to 2013 .A total of 125 ADR cases received classification,statistics and analysis.Results：Digestive system and blood system were main in ADRs,respectively accounted for 80% and 5.6% of the total number of cases.Upper gastrointesti-nal bleeding and thrombocytopenia are the most common lesions. Conclusion：The adverse drug reactions may occur in the clinical use of small doses of aspirin and patients＆#39;medication education should be strengthened.We should pay close attention to adverse reactions and adj ust the method of administration in time,in order to ensure medi-cation safety.

关 键 词：阿司匹林 药物不良反应 合理用药 

分 类 号：R473[医药卫生—护理学]