低分子肝素联合洛伐他汀治疗颈动脉硬化症的临床效果  

Clinical efficacy of low molecular weight heparin combined with lovastatin in treatment of carotid atherosclerosis

作　　者：刘小线 

机构地区：[1]河南省直第三人民医院肾内科,郑州450000

出　　处：《中国当代医药》2014年第25期72-74,共3页China Modern Medicine

摘　　要：目的探讨低分子肝素联合洛伐他汀治疗颈动脉硬化症的临床效果。方法回顾性分析48例颈动脉硬化症患者的临床资料,其中研究组22例患者采用低分子肝素联合洛伐他汀治疗,对照组26例患者采用洛伐他汀治疗,比较两组患者治疗前后颈动脉粥样斑块面积以及颈动脉内膜中层厚度(IMT)。结果两组患者治疗后颈动脉粥样硬化面积和IMT显著缩小(P<0.01),而研究组较对照组缩小更明显(P<0.01)。结论低分子肝素联合洛伐他汀治疗颈动脉硬化症的效果显著,值得临床推广使用。Objective To discuss the clinical efficacy of low molecular weight heparin combined with Lovastatin in treatment of carotid atherosclerosis. Methods Clinical data of 48 cases with carotid atherosclerosis were retrospectively analyzed.22 cases in study group were treated by low molecular weight heparin combined with Lovastatin,and 26 cases in control group were treated by lovastatin.Carotid plaque area and IMT of two groups were compared before and after treatment. Results Carotid plaque area and IMT of two groups decreased apparently after treatment （P〈0.01）,and which of study group decreased more than the control group （P〈0.01）. Conclusion Clinical efficacy of low molecular weight heparin combined with Lovastatin in the treatment of carotid atherosclerosis is remarkable,it is worthy of clinical appli-cation.

关 键 词：低分子肝素 洛伐他汀 颈动脉硬化症 

分 类 号：R543.5[医药卫生—心血管疾病]