三拗片联合头孢呋辛钠治疗肺气肿的疗效观察  

Efficacy Observation of San'ao Tablet Combined with Cefuroxime Sodium in the Treatment of Pulmonary Emphysema

作　　者：张宗林[1] 魏莉[2] 

机构地区：[1]临沂市人民医院药剂科,山东临沂276000 [2]临沂市人民医院呼吸科,山东临沂276000

出　　处：《中国药房》2014年第35期3344-3346,共3页China Pharmacy

摘　　要：目的:观察三拗片联合头孢呋辛钠治疗肺气肿的疗效。方法:选取我院肺气肿患者150例,根据随机数字表法均分为三拗片组、头孢呋辛钠组和联合组。三拗片组患者给予口服三拗片,2粒/次,3次/d;头孢呋辛钠组患者给予静脉滴注含头孢呋辛钠2 g的生理盐水100 ml,2次/d;联合组同时给予三拗片口服和头孢呋辛钠静脉滴注,用法与用量与其他两组一致。3组患者均以1周为1个疗程,治疗2个疗程后,对3组患者的治疗效果及肺功能改善情况进行比较。结果:联合组的总有效率为92.0%,显著高于三拗片组(82.0%)和头孢呋辛钠组(80.0%),差异具有统计学意义(P<0.05);联合组动脉血氧分压(PaO2)、二氮化碳分压(PaCO2)、第1秒用力呼气容积(FEV1.0)和第1秒用力呼气容积占预计值百分比(FEV1%)均优于三拗片组和头孢呋辛钠组,差异具有统计学意义(P<0.05)。结论:三拗片联合头孢呋辛钠治疗肺气肿,疗效较好,患者呼吸功能得到了很大程度的改善。OBJECTIVE：To observe the clinical efficacy of San＇ao tablets combined cefuroxime sodium in the treatment of pulmonary emphysema. METHODS：150 patients with pulmonary emphysema collected from our hospital were randomly divided into San＇ao tablets group,cefuroxime sodium group and combination group. San＇ao tablets group was given San＇ao tablets,2 pieces/time,p.o.,3 times a day;Cefuroxime group was given normal saline containing cefuroxime 100 ml,i. p.,twice a day;Combination group was given San＇ao tablets and normal saline containing Cefuroxime,same usage and dosage as above 2 groups. A treatment course of 3 groups last for a week. After 2 cycles of therapy,therapeutic efficacy and the improvement of pulmonary function were compared among 3 groups. RESULTS：The total effective rate was 92.0% in combination group,which was significantly higher than San＇ao tablets group（82.0%） and cefuroxime sodium group（80.0%）,there was statistical significance（P〈0.05）;PaO2,PaCO2,FEV1.0 and FEV1% of combination group were significantly better than those of other 2 groups,there was statistical significance（P〈0.05）. CONCLUSIONS：San＇ao tablets combined with western medicine antibiotics is effective for pulmonary emphysema and can improve the respiratory function of patients greatly.

关 键 词：三拗片 头孢呋辛钠 肺气肿 

分 类 号：R256.1[医药卫生—中医内科学] R563.3[医药卫生—中医学]