清热利水方联合还原型谷胱甘肽治疗急性肾损伤的疗效分析  

Efficacy of Qingrelishuifang Combined with Reduced Glutathione of the Treatment of Acute Kidney Injury

作　　者：马秀宁[1] 贾刚[1] 李小娟[1] 

机构地区：[1]辽宁省大连市第二人民医院肾内科,辽宁大连116011

出　　处：《中国医药指南》2014年第25期28-29,共2页Guide of China Medicine

摘　　要：目的分析清热利水方联合还原型谷胱甘肽(GSH)治疗瘀热水结型急性肾损伤(AKI)的临床疗效。方法 36例重症患者均在入住ICU病房48 h内发生AKI,随机分为2组,均同时给予抗感染及对症支持治疗,A组18例,为清热利水方联合GSH治疗组,B组18例,为GSH治疗组。分析入住ICU第1、5、7、14天血肌酐、尿素氮、尿量变化情况。结果 2组治疗前后的Scr、BUN及尿量变化均有统计学意义(P<0.05)。结论清热利水方联合GSH对瘀热水结型AKI有确切的疗效。Objective To analyze the effect of Qingrelishuifang and glutathione injection on patients with acute kidney injury（AKI） with the mixed stasis-heat and water syndrome. Methods 36 critical patients appeared AKI within 48 hours of in ICU were divided randomly into two groups.The group A（n=18）was received Qingrelishuifang and glutathione injection.The group B（n：18）was received glutathione injection only.To analyze the difference of Scr、BUN and urine volume respectively in the first、fifth、seventh and 14 th day. Results The difference is of significance in Scr、BUN and urine volume（P〈0.05）.Conclusion Combination of Qingrelishuifang and glutathione injection has marked therapeutic effect on AKI with the mixed stasis-heat and water syndrome.

关 键 词：清热利水方 还原型谷胱甘肽 急性肾损伤 

分 类 号：R692.5[医药卫生—泌尿科学]