Hcy和RDW CV联合检测在急性心肌梗死中的应用价值探讨  

Investigation on the application significance on the combined detection of Hcy and RDW CV in the diagnosis of acute myocardial infarction

作　　者：刘艺军[1] 刘洪亮[2] 徐红[1] 

机构地区：[1]涟水县人民医院检验科,江苏涟水223400 [2]涟水县人民医院心内科,江苏涟水223400

出　　处：《检验医学》2014年第10期989-991,共3页Laboratory Medicine

摘　　要：目的探讨同型半胱氨酸(Hcy)和红细胞体积分布宽度变异系数(RDW CV)联合检测对急性心肌梗死(AMI)诊断的临床价值。方法检测55例AMI患者、60例肺炎患者和60名健康体检者(正常对照组)的Hcy浓度和RDW CV水平,并对结果进行比较分析。结果 AMI组Hcy和RDW CV均明显高于肺炎组和正常对照组(P<0.05);联合检测Hcy和RDW CV对AMI诊断的敏感性为92.0%、特异性为86.1%,明显高于Hcy和RDW CV单项检测的敏感性(82.6%、72.8%)和特异性(80.0%、75.3%)(P<0.05)。结论联合检测血Hcy浓度和RDW CV水平可明显提高AMI诊断的敏感性和特异性。Objective To investigate the clinical significance oi the homocysteine （Hcy） and red blood cell distribution width coefficient of variation （ RDW CV） combined detection in the diagnosis of acute myocardial infarction （AMI）. Methods A total of 55 patients with AMI and 60 patients with pneumonia were enrolled, and 60 healthy subjects were enrolled as control group. The levels of Hcy and RDW CV were determined, and the results were compared. Results In AMI group, Hcy and RDW CV were significantly higher than those of pneumonia and control groups （ P 〈 0.05 ）. The sensitivity- of the combined detection of Hcy and RDW CV in the diagnosis of AMI was 92.0%, the specificity-was 86. 1%, which were higher than those of the single detections of Hcy and RDW CV （82.6%, 72.8% and 80. 0% , 75. 3%） （P 〈 0 05）. Conclusions The combined detection of Hcy and RDW CV can significantly improve the sensitivity- and specificity in the diagnosis of AMI.

关 键 词：同型半胱氨酸 红细胞体积分布宽度变异系数 急性心肌梗死 联合检测 敏感性 特异性 

分 类 号：R446.11[医药卫生—诊断学]