谷胱甘肽在金纳米粒子有序膜表面吸附的表面增强Raman光谱表征  

SERS Study on Adsorption of Glutathione on the Gold Nanoparticle Ordered Film Modified on ITO Thin Glass

作　　者：李甜[1] 曹晓卫[1] 邸佳佳 李玲[1] 王锦锦[1] 

机构地区：[1]上海师范大学化学系,上海200234

出　　处：《光散射学报》2014年第3期233-238,共6页The Journal of Light Scattering

基　　金：国家自然科学基金项目(20775049);上海师范大学创新团队发展计划(DXL122)资助

摘　　要：将制备好的金纳米溶胶粒子组装在3-氨基丙基-三甲氧基硅烷(APTMS)修饰的ITO导电玻璃表面,形成金纳米粒子有序膜。FE-SEM电镜图显示金纳米粒子有序膜呈现出较为均匀的亚单层分布。同时利用电化学方法对有序膜进行了表征。将有序膜作为表面增强Raman光谱(SERS)基底应用于生物分子谷胱甘肽的SERS光谱表征与分析。研究表明,所制备的金纳米粒子有序膜可有效应用于谷胱甘肽分子的SERS光谱表征与分析。Ordered assembled film of gold nanoparticles were prepared by assembling Au nanoparticles on the indium tin oxide（ITO）substrates which had been modified with（3-aminopropyl）-trimethoxysilaine（APTMS）previously.FE-SEM image shows that ordered assembled film of gold nanoparticles was a uniform distribution of the single layer.At the same time electrochemical methods were used to characterize ordered assembled film of gold nanoparticles,it shows good electrochemical properties.Then,ordered assembled film of gold nanoparticles was used for SERS applications.SERS spectra of glutathione was measured and analyzed by using this kind of ordered assembled film.Previous investigations show that the ordered assembled film of gold nanoparticles possesses so good SERS activity and this make it useful for SERS analysis of a wide variety of biomolecules.

关 键 词：金纳米粒子有序膜 表面增强拉曼光谱 ITO导电玻璃 电化学 谷胱甘肽 

分 类 号：O648.15[理学—物理化学]