开放手术与腹腔镜手术治疗大体积前列腺BPH的Meta分析  

Meta-analysis of laparoscopic prostatectomy versus open prostatectomy for benign prostatic hyperplasia with large volume prostate

作　　者：陈晖[1] 汤平[2] 谢克基[2] 欧汝彪[2] 邓向荣[2] 黄马平[1] 刘秋玲[1] 陈湜[1] 

机构地区：[1]广东省工伤康复中心泌尿外科,广州510515 [2]广州医科大学附属广州市第一人民医院泌尿外科,广州510180

出　　处：《广州医药》2014年第5期79-81,共3页Guangzhou Medical Journal

基　　金：广东省科技计划项目(2008B030301004)

摘　　要：目的比较腹腔镜前列腺切除术(laparoscopic prostatectomy,LP)和开放前列腺切除术(Open Prostatectomy,OP)治疗大体积良性前列腺增生(Benign prostatic hyperplasia,BPH)的疗效和安全性。方法检索MedLine、Embase比较LP和OP治疗大体积BPH的文献。采用Revman5.0进行Meta分析。结果纳入文献3篇。术后LP组和OP组患者国际前列腺症状评分(International prostate symptom score,IPSS)、最大尿流率(maximum flow rate,Qmax)比较无统计学差异(P>0.05)。两组间手术时间、前列腺切除重量、术后留置尿管时间和住院时间、术中输血率比较,差异有统计学意义(P<0.05)。两组间尿道狭窄、尿失禁及二次手术发生率比较,差异无统计学意义(P>0.05)。结论 LP和OP对大体积前列腺BPH有相同的近期疗效。LP组手术时间长、切除前列腺组织少,但是术后膀胱冲洗时间、留置尿管时间、住院时间短。Objective To compare laparoscopic prostatectomy LP with Open prostatectomy OP for benign prostatic hy-perplasia with large volume. Methods The literature were identified systematically using Medline,Embase.Meta-analysis was performed by Review Manager 5.0. Results 3 CCTs were included.There was no significant difference between LP and OP in terms of IPSS,Qmax（P 〉0.05）.LP was associated with less blood loss,a shorter irrigation,catheterization and hospital stay time except longer operating time.LP and OP were similar in terms of urethral stricture,incontinence,transfusion require-ment and rate of re-intervention. Conclusion LP served a significant improvement in IPSS,Qmax as well as OP.Although more operating time and less resected tissue,LP has several advantages over OP.It was as safe as OP in terms of adverse events.

关 键 词：腹腔镜前列腺切除术 开放前列腺切除术 大体积良性前列腺增生 疗效和安全性 META 分析 

分 类 号：R699.8[医药卫生—泌尿科学]