原子吸收光谱法测定四季感冒片铬含量  

Determination of Chromium in Sijiganmao Tablets by Atomic Absorption Spectrometry

作　　者：郑兆显 张朋 赵丹彤 

机构地区：[1]菏泽市食品药品检验中心,山东菏泽274000 [2]山东省鲁南药物研究院,山东菏泽274000

出　　处：《食品与药品》2014年第5期357-359,共3页Food and Drug

摘　　要：目的测定市场上四季感冒片铬含量,为制定四季感冒片标准提供参考数据。方法采用硝酸浸泡过夜,微波消解,石墨炉原子吸收光谱法测定。结果线性相关系数为0.9981,加样回收率96.9%,检出限0.41 ng/mL,重复性RSD为1.6%(n=6)。结论此法可用于四季感冒片质量控制,结果表明,市场上四季感冒片铬含量潜在风险较低。Objective To develop a method for determination of chromium in Sijiganmao Tablets by atomic absorption spectrophotometry, to provide basis for quality specification formulation. Methods The sample was detected by graphite furnace atomic absorption spectrometry after soaking in nitric acid overnight and microwave digestion. Results The linear correlation coefficient is 0.9981, and the average recovery is 96.9 %. The detection limit is 0.41 ng/ mL, and RSD of repeatability test is 1.6 %（n=6）. Conclusion This method can be used in quality control of Sijiganmao Tablets. Sijiganmao Tablets on the market are of low risk of chromium content.

关 键 词：原子吸收光谱法 四季感冒片 铬 含量测定 

分 类 号：R917[医药卫生—药物分析学]