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机构地区:[1]中国医科大学附属第一医院产科,辽宁沈阳110001
出 处:《中国实用妇科与产科杂志》2014年第10期766-769,共4页Chinese Journal of Practical Gynecology and Obstetrics
摘 要:为了维持妊娠的正常进行、胎儿生长发育、产后哺乳等特殊需求,孕期必须有一定量的脂肪储备。正常妊娠期间血脂高于正常,但研究表明,子痫前期患者较正常孕妇血脂水平明显增高。血脂异常可能通过氧化应激、炎性反应等损伤血管内皮细胞功能,引起子痫前期的发展。孕前早期通过饮食控制、运动干预及必要的药物治疗控制血脂在正常范围,并且孕期合理饮食、适当运动对预防子痫前期的发生具有重要作用,但孕期药物降脂是否合理仍需大量证据进一步证实。In order to maintain the pregnancy, fetal growth and development, postpartum nursing and other special requirements, a certain amount of fat reserving during pregnancy is important. But the study showed that compared with normal pregnant women,the blood lipid level in patients with preeclampsia increases obviously. Dyslipidemia may cause the development of preeclampsia through oxidative stress, inflammatory reaction and so on,which damages vascular endothelial cell function.So early intervention and blood lipids control through diet and exercise intervention and necessary medication is necessary, and a reasonable diet and proper exercise during pregnancy plays an important role in the prevention of preeclampsia, but lipid-lowering drugs during pregnancy still needs a lot of evidence to confirm.
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