体质指数和老年男性骨质疏松症的相关性分析  

Association of body mass index and male primary osteoporosis

作　　者：林吉生[1] 马钊[1] 费琦[1] 王炳强[1] 杨雍[1] 赵凡[1] 王奇[1] 

机构地区：[1]首都医科大学附属北京友谊医院骨科,100050

出　　处：《中华医学杂志》2014年第33期2593-2596,共4页National Medical Journal of China

基　　金：2013北京市科学技术委员会“首都市民健康项目培育”（Z131100006813040）;北京友谊医院科研启动基金（yyqdkt2011-12）

摘　　要：目的 研究体质指数与老年男性骨质疏松症发生、发展的相关性.方法 2010年9月至2013年12月北京友谊医院骨科查体并接受双能X线骨密度（DXA）检查的北京地区老年男性受检者276例,记录腰椎总（L1-4）、左侧股骨颈和左全髋的骨密度T值,测量、记录身高和体重并计算体质指数,根据WHO诊断标准将研究对象分为骨质疏松组、骨量减少组和骨质正常组,根据不同体质指数将老年男性分为3组：体重过低组、体重正常组、超重及肥胖组.分析体质指数与不同部位骨密度T值的相关性,比较不同体质指数组间骨质疏松症患病率是否存在显著差异,采用ROC曲线评价体质指数预测男性骨质疏松及骨量减少的诊断价值.结果 体质指数与老年男性不同部位的骨密度T值之间存在着正相关（r=0.141 ～0.237,P＜0.05）;体重过低组骨质疏松症患病率为50.0％（6/12）,体重正常组骨质疏松症患病率为17.4％ （21/121）,超重及肥胖组骨质疏松症患病率为12.6％ （18/143）,三组间差异有统计学意义（xtrend2=5.02,P＜0.05）;ROC曲线分析提示体质指数预测男性骨质疏松和骨量减少的价值有限（P＞0.05）.结论 体质指数和老年男性原发性骨质疏松症存在一定的相关性,但其预测男性骨质疏松症的价值有限.Objective To explore the association between body mass index （BMI） and male primary osteoporosis （OP） in a Chinese Han population.Methods The association of BMI with OP was assessed in 276 Chinese healthy aged males for physical examination.They were classified into OP,osteopenia and normal groups according to the World Health Organization （WHO） criteria,i.e.OP was defined arbitrarily when any T-score was-2.5 standard deviations or less at femoral neck,total hip or lumbar spine （L1-4） site.We also classified the subjects as different BMI groups of low weight,normal weight,overweight and obesity.The prevalence of OP was compared among different BMI groups.We determined the sensitivity,specificity and area under the curve of receiver operating characteristic （ROC）for validating the valuation of BMI to predict male primary OP.Results Among them,6/12 had OP in the low weight group,17.36％ （21/121） in the normal group and 12.59％ （18/143） in the overweight and obesity group.And the difference was significant.The analysis of ROC curve showed that BMI was of limited value in predicting OP （P ＞ 0.05）.Conclusion BMI has a positive correlation with male OP.The value of BMI is limited for predicting OP in males.And the relevant factors associated with male OP should to be further studied.

关 键 词：人体质量指数 骨质疏松 男人 

分 类 号：R580[医药卫生—内分泌]