体外冲击波治疗勃起功能障碍及阴茎硬结症的研究进展  

Extracorporeal shockwave therapy for erectile dysfunction and Peyronie's disease

作　　者：朱霁银 姜睿 

机构地区：[1]泸州医学院附属医院医学实验中心 [2]泌尿外科,四川泸州646000

出　　处：《中华男科学杂志》2014年第9期846-849,共4页National Journal of Andrology

基　　金：国家自然科学基金(81070486/H0415);四川省卫生厅基金(090214);四川省杰出青年基金(2010JQ0040)~~

摘　　要：阴茎海绵体血管内皮受损、血管舒缩功能障碍、血流量不足是引起勃起功能障碍(ED)的重要病因。目前对ED的治疗主要应用5-型磷酸二酯酶抑制剂(PDE5I),但对部分ED患者无效。由阴茎硬结病(PD)引起的ED除使用PDE5I,还可采取手术、电疗等物理疗法,但疗效难以保证。近年发现低强度体外冲击波治疗(LI-ESWT)能促进血管再生,提高阴茎海绵体血流量,有望成为治疗ED和PD的一项有效的新方法。Penile vascular endothelial damage, vasomotor dysfunction, and blood flow deficiency are the major causes of erectile dysfunction （ED）. Current management of ED mostly depends on selective phosphodiesterase type 5- （ PDE5 ） inhihitors, which fail for some ED patients. For Peyronie＇s disease-induced ED, surgical and physical therapies are used in addition to PDE5I medication, but frequently it is difficult to achieve satisfactory results. Recent studies show that the low-intensity extracorporeal shockwave therapy can promote angiogenesis and improve blood flow to the penis, which promises to he a novel effective therapy for ED and Peyronie＇s disease.

关 键 词：体外冲击波 勃起功能障碍 阴茎硬结症 血管再生 

分 类 号：R698.1[医药卫生—泌尿科学] R697.171[医药卫生—外科学]