空肠弯曲菌的流行病学调查及其在夏季腹泻患者中的检出率  

Epidemiological investigation of Campylobacte jejuni and its detection in patients with summer diarrhea

作　　者：袁敏[1] 曾永鸿[2] 陈志国[1] 李晶[1] 赵欣 

机构地区：[1]南阳理工学院张仲景国医学院,河南省南阳市473004 [2]信阳职业技术学院医学院解剖教研中心,河南省信阳市464000 [3]淅川县教体局,河南省淅川县474450

出　　处：《世界华人消化杂志》2014年第24期3705-3709,共5页World Chinese Journal of Digestology

摘　　要：目的:探讨空肠弯曲菌在夏季腹泻患者中的检出情况.方法:回顾性分析南阳理工学院附属医院2012与2013年收治的夏季腹泻患者空肠弯曲菌的检出情况,分析空肠弯曲菌阳性患者性别、年龄、诊区及月份分布特点.结果:2012与2013年空肠弯曲菌阳性率均显著高于结肠弯曲菌(6.14%vs 0.16%,6.20%vs0.14%),差异具有统计学意义(P<0.05);2012与2013年空肠弯曲菌阳性率比较(6.14%vs6.20%),差异无统计学意义(P>0.05);2012与2013年夏季腹泻患者男性空肠弯曲菌阳性率均高于女性(6.46%vs 5.60%,6.52%vs5.62%),但差异无统计学意义(P>0.05);2012年与2013年夏季腹泻患者空肠弯曲菌阳性率年龄分布主要集中于<1岁和16-45岁,但不同年龄段阳性率比较(9.33%,3.31%,6.25%,6.60%,2.44%vs 2.17%,9.36%,2.84%,6.35%,6.72%,1.96%vs 0.00%),差异无统计学意义(P>0.05);2012与2013年夏季腹泻患者门诊部空肠弯曲菌阳性率均显著高于住院部(7.56%vs 2.37%,7.82%vs 2.40%),差异具有统计学意义(P<0.05);2012、2013年夏季腹泻患者不同月份间空肠弯曲菌阳性率比较(6.00%,6.28%vs 6.14%,6.09%,6.33%vs 6.17%),差异无统计学意义(P>0.05);2012与2013年夏季腹泻患者空肠弯曲菌阳性率均显著高于南阳理工学院张仲景国医学院2012年临床资料中冬季患者空肠弯曲菌阳性率(6.14%vs1.82%,6.20%vs 1.82%),差异具有统计学意义(P<0.05).结论:空肠弯曲菌为引起夏季腹泻的主要致病菌之一,其流行病学分布具有多样性和复杂性.AIM： To analyze the detection of Campylobactejejuni in patients with diarrhea.METHODS： The detection of Campylobacte jejuniin patients with diarrhea was analyzed retro-spectively. The clinical characteristics includ-ing patient sex, age, area for examination, andmonth distribution were analyzed.RESULTS： The positive rate of Campylobacte jeju-ni was higher than that of Campylobacter coli in theyears of 2012 and 2013（6.14% vs 0.16%, 6.20% vs0.14, P 〈0.05）. There was no significant differencefor the detection rate of Campylobacte jejuni be-tween the years of 2012 and 2013（6.14% vs 6.20%, P 〈0.05）. The positive rates of Campylobacte jejuni in males were higher than those in females in pa-tients with summer diarrhea in the years of 2012 and 2013, but the differences were not significant（6.46% vs 5.60%, 6.52% vs 5.62%, P 〉0.05）. The detection of Campylobacte jejuni in patients with summer diarrhea in the years of 2012 and 2013 was mainly distributed in the age groups of 1 and 16-45 years, although there were no signifi-cant differences in the positive rates between dif-ferent age groups（9.33%, 3.31%, 6.25%, 6.60%, 2.44% vs 2.17%; 9.36%, 2.84%, 6.35%, 6.72%, 1.96% vs 0.00%, P 〈0.05）. The positive rates of Campylo-bacte jejuni in the years of 2012 and 2013 were sig-nificantly higher in out-patients than in inpatients（7.56% vs 2.37%, 7.82% vs 2.40%, P〉0.05）. The positive rates of Campylobacte jejuni in the years of 2012 and 2013 showed no significant differences among different months（6.00%, 6.28% vs 6.14%; 6.09%, 6.33% vs 6.17%, P 〈0.05）. The positive rates of Campylobacte jejuni in summer in the years of 2012 and 2013 were significantly higher than those in the winter of 2012（1.82%, 6.14% vs 1.82%, 6.20% vs 1.82%, P〉0.05）.CONCLUSION： Campylobacte jejuni was one of the major pathogens of summer diarrhea.

关 键 词：空肠弯曲菌 夏季腹泻 流行病学 

分 类 号：R181.3[医药卫生—流行病学] R574[医药卫生—公共卫生与预防医学]