石家庄地区耐多药肺结核病患者耐药情况及相关因素分析  

Drug resistance situation and influencing factors analysis of multidrug-resistant tuberculosis patients in Shijiazhuang area

作　　者：李亚楠[1] 何立新[1] 朱建良[1] 郭付爱[1] 张红军[1] 赵子运[1] 

机构地区：[1]石家庄市疾病预防控制中心,河北050011

出　　处：《医学动物防制》2014年第8期845-847,共3页Journal of Medical Pest Control

摘　　要：目的探索耐多药肺结核病(MDR-TB)的成因。方法对实验室检测出的57例耐多药肺结核患者的耐药情况、肺部病变及合并症以及相关因素进行分析。结果 57例耐多药患者中,复治患者40例,初治患者17例,耐≥3种抗结核药物的患者占84%;男性高于女性,以20～30岁年龄组最多,农村高于城市;中断治疗的患者39例,高于坚持治疗的患者18例。结论耐多药患者中多数患者为复治患者且有中断治疗史,耐多药患者受性别、年龄、职业、居住地、治疗史等方面影响。应针对相关影响因素,采取有效措施,控制耐多药肺结核病的发生。Objective To investigate the cause of formation on multi - drug resistant tuberculosis （ MDR - TB） . Methods The status of drug resistance, lung lesions with complications and influencing factors of 57 MDR - TB patients were analyzed with TB drug susceptibility test. Results Among 57 MDR - TB patients, there were 40 treated patients, 17 untreated patients, there were 84% of the patients resistance to ≥13 kinds of anti -TB drugs, male higher than the female, 20 - 30 years old age group take the most, rural higher than the city; 39 treatment interrupted patients, higher than the continue treatment patients of 18. Conclusions Among the MDR - TB patients, most patients with history of treatment and break off period, the incidence of MDR - TB is as- sociated with gender, age, occupation, place of residence, and history of tuberculosis treatment; We should aim to the related influencing factors, take necessary measures, to prevent the occurring of multi - drug resist- ance tuberculosis.

关 键 词：耐多药肺结核病 耐药 患者 

分 类 号：R521[医药卫生—内科学]