调控炎性细胞因子对骨修复的影响  

Influence of Regulating Inflammation Factors on Bone Repair

作　　者：郝健明[1] 练克俭[1] 

机构地区：[1]中国人民解放军第一七五医院骨科医院,福建漳州363000

出　　处：《医学综述》2014年第18期3301-3303,共3页Medical Recapitulate

摘　　要：炎症是一个井然有序的生物反应,在骨折或损伤后促进骨修复中起着直接和关键的作用。然而,在一些临床情况中,如炎症性疾病或植入医学材料的严重异物反应,不但使原先的炎性反应没有解决,反而会加重或造成慢性炎症,严重影响骨组织生成。因此,该文将总结体内外研究中炎症及调节炎症的细胞因子对骨修复的影响和调控,并认识其在该领域的重要性。Inflammation is an immediate response that plays a critical role in healing after fracture or injmy to bone.However,in certain clinical cases,such as inflammatory diseases or severe transplant rejection after implantation of a biomedical device,the inflammatory response may become chronic and result in destructive catabolic effects on the bone tissue.Here is to make a review on how inflammation and factors that regulate the inflammation impact on and regulate the bone regeneration according to recent in vitro and in vivo studies,so as to get better understanding to its importance.

关 键 词：炎症 骨 修复 成骨细胞 破骨细胞 

分 类 号：R683[医药卫生—骨科学]