穿山龙中原薯蓣皂苷的提取工艺研究  

The extraction technique of protodioscin in Dioscorea nipponica Mak.

作　　者：王洁雪[1] 刘军[2] 丁克毅[2] 

机构地区：[1]成都师范学院化学与应用化学系,四川成都611113 [2]西南民族大学少数民族药物研究所,四川成都610041

出　　处：《西南民族大学学报（自然科学版）》2014年第5期696-700,636,共5页Journal of Southwest Minzu University(Natural Science Edition)

摘　　要：目标:优选穿山龙中原薯蓣皂苷的提取工艺.方法:采用正交试验法,以提取液中原薯蓣皂苷的含量作为指标,研究了提取溶媒、料液比、提取时间、提取次数四种因素对原薯蓣皂苷的提取影响;考察5种不同型号的大孔树脂对原薯蓣皂苷的吸附性能.结果:溶媒是提取原薯蓣皂苷的主要因素,最佳提取工艺为A3D2B3C2,AB-8型大孔树脂对原薯蓣皂苷的吸附性能最佳.结论:该工艺能较好的富集原薯蓣皂苷,具有一定的工业应用前景.Objective： To explore the optical extraction process for protodioscin from Dioscorea nipponica Mak. Method： Taking protodioscin content in extract as the index, the orthogonal test method was used to study the influence of solvent, solid-liquid ratio, extraction times and time. Choosing 5 different typical macroporous resin for separation and purification of protodioscin, the influence of static adsorption were studied. Results： Solvent was the main factor of extracting protodioscin, the optimal conditions were A3D2B3C2 and the best resin for adsorption is AB-8. Conclusion： The process is feasible to enrich protodioscin and has great potential for industrial application.

关 键 词：穿山龙 原薯蓣皂苷 正交试验 大孔树脂 

分 类 号：R284[医药卫生—中药学] R93[医药卫生—中医学]