羚角钩藤汤加减联合西药预防小儿高热惊厥复发临床疗效观察  

Study on Clinical Efficacy of Antelope Horn Uncaria Decoction with Western Medicine with Recurrence Infantile Febrile Convulsion

作　　者：陈国庆[1] 金李君[1] 

机构地区：[1]浙江省人民医院,浙江杭州310014

出　　处：《中华中医药学刊》2014年第10期2538-2540,共3页Chinese Archives of Traditional Chinese Medicine

摘　　要：目的:探讨羚角钩藤汤联合安定预防小儿高热惊厥(FC)复发的疗效,为提高临床治疗提供依据。方法:将易发高热惊厥患儿64例按照随机数字表法分为观察组(32例)和对照组(32例)。当患儿再次出现发热时,两组组接受常规退热药物和安定治疗,观察组在此基础上接受羚角钩藤汤加减方,比较两组的总疗效。结果:观察组发热次数为(12.43±5.64),惊厥次数为(1.12±0.46),复发例数为4例,癫痫次数为1例;对照组发热次数为(11.78±6.21),惊厥次数为(2.93±0.76),复发例数为8例,癫痫次数为3例。观察组惊厥次数、复发例数、癫痫次数都明显低于对照组(t=1.37,χ2=4.03,χ2=4.07,P<0.05)。观察组发热次数较对照组无统计学差异(t=0.02,P>0.05)。对照组不良反应发生率为15.6%;观察组的不良反应发生率为6.25%。观察组的不良反应发生率高于对照组(P<0.05)。结论:羚角钩藤汤联合安定可有效降低小儿高热惊厥复发率。Objective： To investigate the clinical efficacy of Antelope Horn Uncaria Decoction with western medicine on the treating 63 patients with recurrence infantile febrile convulsion. Methods： 64 cases of children with febrile seizures were randomly divided into observation group（n = 32） and the control group（n = 32）. When patients got fever again,two groups received conventional antipyretic drugs and diazepam treatment. The observation group received Antelope Horn Uncaria Decoction. The drug was retreated after the fever disappeared. The follow- up lasted 1 year. And then the overall effects of the two groups were compared. Results： In observation group,the number of fever was（12. 43 ± 5. 64）. The number of convulsions was（1. 12 ± 0. 46）. The number of recurrence was 4. The number of epilepsy was one case. In control group,the number of fever was（11. 78 ± 6. 21）. The number of convulsions was（2. 93 ± 0. 76）. The number of recurrence was eight cases. The number of epilepsy was three. The number of convulsions,the number of recurrence and the number of seizures in observation group were significantly lower than those of the control group（t = 1. 37,χ2= 4. 03,χ2= 4. 07,P〈0. 05）. The number of fever between these two group had no significant difference（t = 0. 02,P〉0. 05）.Adverse reactions occurring in the control group was 15. 6%. The adverse reactions observed group was 6. 25%. Incidence of adverse reactions in observation group was lower than that of the control group（P〈0. 05）. Conclusion： The Antelope Horn Uncaria Decoction combined with western medicine showed better effect and reduced the recurrence rate of febrile seizures in infant.

关 键 词：羚羊角 安定 惊厥 复发 

分 类 号：R246.4[医药卫生—针灸推拿学]