电针与帕罗西汀治疗惊恐障碍的临床疗效  

Clinical efficacy for electro-acupuncture and paroxetine in treatment of panic disorder

作　　者：宋薇薇[1] 晏兰[1] 周虎 

机构地区：[1]解放军94医院门诊部,江西南昌330002 [2]解放军94医院中医科,江西南昌330002

出　　处：《药学实践杂志》2014年第5期376-378,共3页Journal of Pharmaceutical Practice

摘　　要：目的比较电针疗法与帕罗西汀片治疗惊恐障碍的疗效和安全性。方法将59例随机分为电针组(30例)和帕罗西汀组(29例),疗程为4周。在治疗前及治疗1、2、4、8周时采用焦虑自评量表(SAS)、汉密尔顿抑郁量表(HAMA)、疗效指数(CGI-EI)、Barthel指数(BI)量表评定疗效和不良反应。结果电针组总有效率为86.66%,帕罗西汀组为82.76%,两组疗效差异无统计学意义;疗效指数及起效时间两组间有显著差异,电针组起效时间短、不良反应少。结论两种方法治疗惊恐障碍疗效相当,但电针疗法起效时间短、疗效指数高、不良反应少。Objective To compare the efficacy and safety of the treatment of panic disorder by electro-acupuncture（ EA） and paroxetine. Methods 59 patients were randomly divided into paroxetine group（ 30 cases） and EA group（ 29 cases）,the therapeutic course was 4 weeks. SAS,HAMA,CGI-EI,BI scale were given to evaluate the efficacy and adverse reactions at 1,2,4 weekend before treatment and after treatment. Results EA group total effective rate was 86. 66%,the paroxetine group total effective rate was82. 76%,the two groups total efficacy difference was not statistically significant; efficacy index and onset time between the two groups had significant differences. Conclusion The overall curative effects were similar in patients of the two groups,but onset short electro-acupuncture,the curative effect was high and adverse reactions were fewer.

关 键 词：帕罗西汀 电针 惊恐障碍 

分 类 号：R971[医药卫生—药品]