配比油对高脂血症家兔红细胞脂肪酸影响的研究  

Study of Proportioning Oil Effects on Erythrocyte Fatty Acids in Rabbits with Hyperlipemia

作　　者：沈晓京[1] 赖炳森[1] 吴红梅[1] 张玲[1] 孙树秦[1] 

机构地区：[1]解放军北京军医学院生化教研室,北京100071

出　　处：《中国公共卫生》2002年第8期918-920,共3页Chinese Journal of Public Health

基　　金：全军"九五"医药卫生科研基金资助课题 (编号 :96D0 69)

摘　　要：目的　研究配比油对高脂血症家兔红细胞脂肪酸的影响。方法　用气相色谱法测定 5 0只家兔喂食天然配比油 3个月中红细胞脂肪酸组分和含量的动态变化。结果　高脂对照组的 18∶1和MUFA明显增高 ,摄入高脂饲料和配比油的 3个实验组的α18∶3水平明显增高 ,实验Ⅰ组的α18∶3含量最高 ;实验Ⅱ组和实验Ⅲ组的γ18∶3和 18∶2明显增高、18∶1和MUFA无明显变化。结论　补充 3种配比油均可提高体内n3 系多烯脂酸水平 ,配比 2油还可保持体内n6/n3 的动态平衡 ,配比 2和配比Objective To explore the proportioning oils effects on erythrocyte fatty acids in rabbits with hyperlipemia.Methods Change of the components and contents of erythrocyte fatty acids in 50 rabbits fed on the natural proportioning oils on three months were determined by GC method.Results The oleic acid (18∶1) and monounsaturated fatty acids(MUFA) were apparently increased in hyperlipemia control group. The level of α-linolenic acid (α18∶3) was apparently increased in three test groups after being fed on the hyperlipemia forage and the proportioning oils. The highest content of α18∶3 was showed in test I group and the contents of γ-linolenic acid (γ18∶3) and linoleic acid (18∶2) were apparently increased in test Ⅱ and group Ⅲ in which 18:1 and MUFA were no significantly change.Conclusion The level of n 3 polyunsaturated fatty acid may be increased by supplement of three proportioning oils. The dynamic balance of n 6/n 3 ratio may also be kept in the body by supplement of the proportioning 2 oil. The proponioning 2 and 3 oils have more fairly good effect on prevention and treatment of hypelipemia.

关 键 词：酯比油 高脂血症 家兔 红细胞脂肪酸 

分 类 号：R589.2[医药卫生—内分泌]