糖尿病合并血源性感染90例临床分析  

Clinical Analysis of 90 Diabetic Patients with Bloodstream Infection

作　　者：刘凤[1] 肖虎[1] 云鹏[1] 

机构地区：[1]湖北省荆州市第一人民医院内分泌科,湖北荆州434000

出　　处：《医学临床研究》2014年第8期1564-1566,共3页Journal of Clinical Research

摘　　要：【目的】探讨糖尿病（DM）患者合并血源性感染的病原学分布和临床特征。【方法】对本院90例DM合并血源性感染患者的临床资料进行回顾性分析。【结果】DM患者合并菌血症以大肠埃希菌最为常见，其次为葡萄球菌属和肺炎克雷伯杆菌，各占比为44．4％、27．7％和15．6％，真菌的检出率为1．1％；DM 患者合并脓毒血症的致病菌依次为肺炎克雷伯菌、金葡菌、大肠埃希菌及其他，各占比为45．8％、20．8％、20．8％及12．6％。与非脓毒血症者比较，脓毒血症者的年龄大、发热时间长、糖化血红蛋白（HbA1c）高、C反应蛋白（CRP）高、血脂指标低，且两组比较有显著性差异（P＜0．01，P＜0．05）。【结论】应重视DM 合并血源性感染的特殊性，以指导临床的诊治。[Objective]To explore the distribution of pathogens and clinical characteristics of diabetes mellitus（DM ） patients with bloodstream infection .[Methods] Clinical data of 90 DM patients with bloodstream infection in our hospital were analyzed retrospectively .[Results] The most common pathogens of DM patients with bacteremia were Escherichia coli followed by Staphylococcus and Klebsiella pneumonia ,which accounted for 44 .4% ,27 .7% and 15 .6% respectively ,and the detection rate of fungi was 1 .1% .The pathogens of DM patients with sepsis were Klebsiella pneumonia ,Staphylococcus ,Escherichia coli and others in turns ,which accounted for 45 .8% ,20 .8% ,20 .8% and 12 .6% ,respectively .Compared with DM patients without sepsis , patients with sepsis were older ,long duration of fever ,high level of HbA1c ,high C-reactive protein （CRP） and low serum lipids ,and there was significant difference between two groups（ P 〈0 .01 ,P 〈0 .05） .[Conclusion] The specificity of DM combined with bloodstream infection should be emphasized so as to guiding clinical diagnosis and treatment .

关 键 词：糖尿病/并发症 菌血症/并发症 菌血症/微生物学 毒血症/并发症 毒血症/微生物学 埃希氏菌属/致病力 克雷伯菌  肺炎/致病力 葡萄球菌  金黄色/致病力 回顾性研究 

分 类 号：R587.1[医药卫生—内分泌]