超声电导药物透入治疗骨和关节结核  

作　　者：兰远波[1] 刘权贤 黄璐[1] 王盛兰[1] 张建勇[1] 陈玲[1] 

机构地区：[1]遵义医学院附属医院呼吸二科,563003

出　　处：《临床医药文献电子杂志》2014年第5期14-14,44,共2页Electronic Journal of Clinical Medical Literature

基　　金：贵州省结核病综合防治2011协同创新中心(培育)项目;贵州省第五批科技创新人才团队[黔科合(2012)4011]

摘　　要：目的了解低频超声电导药物透入治疗骨、关节结核的临床疗效,方法回顾性分析26例骨、关节结核患者通过给予全身抗结核化疗同时联合应用超声电导透入异烟肼和利福平治疗疗效,其中1例脊柱结核患者因不能耐受全身抗结核药物毒副作用仅给予局部超声电导药物透入治疗。分析治疗2周、1月、2月、6月和9月后患者临床症状、局部包块和影像学病灶吸收情况。结果 26例骨、关节结核通过口服抗结核联合局部EP治疗病灶得到不同程度吸收,其中仅接受局部超声电导药物透入的脊柱结核患者治疗9个月后病灶明显吸收。结论抗结核药局部超声电导透入治疗骨、关节结核病临床疗效确切,值得推广。Objective：To observe the effect of low-frequency Electro- phonophoresis（EP） on patients with bone and joint tuber-culosis. Methods：26 patients with bone and joint tuberculosis were retrospectively analyzed by systemic chemotherapy anti-tuberculosis drugs and EP with isoniazid and rifampicin, among these, 1 case with spinal tuberculosis was only treated by EP with isoniazid and ri-fampicin because of intolerance to side effects from oral anti-tuberculosis drugs. The clinical symptoms, local situation and the changes of ra-diographic lesions were observed at 2 weeks, 1 , 2 , 6 and 9 months. Result：The clinical symptoms, local situation and the changes of radio-graphic lesions of 26 patients with bone and joint tuberculosis were improved at different levels based on the treatment period after treatment with systemic chemotherapy anti-tuberculosis drugs and EP with isoniazid and rifampicin, one of them treated only with EP recovered well. Conclusion：low-frequency Electro-phonophoresis effects on patients with bone and joint tuberculosis and deserves to be used widely.

关 键 词：超声电导药物透入 异烟肼 利福平 骨结核 关节结核 

分 类 号：R529.5[医药卫生—内科学]