枫蓼肠胃康胶囊抗腹泻作用的实验研究  

Experimental Study on Anti-diarrhea Effect of Fengliao Changweikang Capsule

作　　者：卢丽珠[1] 俞进[1] 

机构地区：[1]杭州市中医院,杭州310007

出　　处：《中国中医药科技》2014年第5期499-500,507,共3页Chinese Journal of Traditional Medical Science and Technology

基　　金：浙江省中医药科技计划项目No.2009GA009

摘　　要：目的:观察枫蓼肠胃康胶囊的抗腹泻作用,为临床应用提供实验依据。方法:通过蓖麻油致小鼠腹泻模型、小肠推进实验以及大鼠肠腔积液实验,以抗腹泻指数、碳粉推进率、肠腔积液体积为指标,观察枫蓼肠胃康胶囊的作用。结果:枫蓼肠胃康胶囊可明显提高抗腹泻指数,并可明显地抑制正常小鼠的小肠推进运动,减少腹泻大鼠的肠腔积液体积,并呈现出一定的剂量依赖性。结论:枫蓼肠胃康胶囊具有良好的抗腹泻作用。Objective：To observe the anti-diarrh ea effect of Fengliao changweikang capsule.Methods：Anti-diarrhoeal activity of Fengliao changweikang capsule was evaluated using castor oil -induced diarrhea , charcoal meal transit and castor oil -induced enteropooling in different group mice.Results：Fengliao changwei-kang capsule dose -dependently and significantly increased anti -diarrhea index , decreased the frequency of defecation , decreased the volume of castor oil -induced intestinal fluid secretion.Conclusion：Fengliao chang-weikang capsule possesses anti -diarrhoeal effect in mice.

关 键 词：腹泻 枫蓼肠胃康胶囊 抗腹泻指数 小肠推进率 肠腔积液 

分 类 号：R285.5[医药卫生—中药学]