埃博拉出血热研究现状及2014年疫情进展  

Research advances in Ebola virus disease and disease update in the 2014 Ebola outbreak

作　　者：张云辉[1] 王姝[1] 陈玉琪[1] 李军[1] 

机构地区：[1]<传染病信息>杂志社,北京100039

出　　处：《传染病信息》2014年第4期I0003-I0008,共6页Infectious Disease Information

摘　　要：发现于1976年的埃博拉出血热具有高传染性、高致病性和高病死率的特点，曾多次在非洲中西部暴发流行，病死率高达50％-90％。然而目前仍然未研制出有效的疫苗和抗病毒药物。始于2014年初的非洲西部暴发疫情是该病历史上最严重的疫情，感染和死亡人数已经超过了该病发现以来的总和，WHO宣布本次疫情为“国际关注的突发公共卫生事件”。国际公共卫生和医疗部门正在通力合作抗击这一烈性传染病。本文就该病研究现状及本次疫情暴发以来的一些特点进行回顾。Ebola virus disease （EVD） is a severe, often fatal illness in humans, with high infectivity, high pathogenicity and high mortality rate. It first appeared in 1976, and several outbreaks of EVD have occurred in Western and Central Mrica, with a case fatality rate of 50%-90%. However, no licensed vaccine and antiviral agent for EVD are available for use. The outbreak occurring in Western Mrica in 2014 is the most severe outbreak of EVD in history, and the number of the infected and dead cases is larger than the total number of those cases in the previous outbreaks of EVD. WHO declared the 2014 Ebola outbreak to be an international public health emergency, and currently, international public health and medical settings are making common efforts to com- bat this virulent disease. The authors of this article summarize the research advances in EVD and the features of the 2014 Ebola out- break.

关 键 词：传染病 出血热 埃博拉 治疗学 综合预防 

分 类 号：R512.8[医药卫生—内科学]