妊娠早期亚临床甲状腺功能减退与妊娠糖尿病的相关性研究  

Relationship of subclinical hypothyroidism with gestational diabetes mellitus during early pregnancy

作　　者：李春莉[1] 黄卉[1] 李秋红[1] 

机构地区：[1]重庆市妇幼保健院检验科,400013

出　　处：《中华内分泌代谢杂志》2014年第9期747-748,共2页Chinese Journal of Endocrinology and Metabolism

摘　　要：对2320名早期妊娠（孕周＜12周）妇女进行甲状腺功能筛查,统计分析亚临床甲状腺功能异常的患病率,并进一步分析其与妊娠糖尿病的相关性.结果显示,2 320名妊娠早期妊娠妇女中,临床及亚临床甲状腺功能减退（甲减）共234例,患病率为10.1％,其中临床甲减8例,占全部妊娠妇女的0.34％;亚临床甲减226例,占9.74％.甲状腺功能亢进14例,患病率为0.6％.亚临床甲减组中有33.3％发生妊娠糖尿病,明显高于正常对照组12.9％.提示妊娠早期亚临床甲减可明显升高妊娠糖尿病的发生率,因此,孕早期进行甲状腺功能筛查尤为重要.A screening of thyroid function was performed in 2 320 pregnant women whose gestational age was less than 12 weeks.The incidence of subclinical thyroid disease and its relationship with gestational diabetes mellitus were analyzed.The results showed that there were 8 patients （0.34％） with clinical hypothyroidism,226 （9.74％） with subclinical hypothyroidism,and 14 patients （0.6％） with hyperthyroidism among 2 320 pregnant women.The prevalence of gestational diabetes mellitus in pregnant women with subclinical hypothyroidism was apparently higher than that in normal pregnant women （33.3％ vs 12.9％,P＜0.05）,suggesting that the increased incidence of gestational diabetes mellitus seems to be related to subclinical hypothyroidism during early pregnancy.Therefore,it is important to screen the function of thyroid during early pregnancy

关 键 词：甲状腺功能减退 亚临床 妊娠糖尿病 

分 类 号：R714.256[医药卫生—妇产科学]