重庆市35岁及以上人群代谢综合征的流行病学调查  

The prevalence of metabolic syndrome in residents aged over 35 years in Chongqing

作　　者：邓敏[1] 邓华聪[1] 王行[1] 瞿华[1] 陈晨[1] 刘芳[1] 

机构地区：[1]重庆医科大学附属第一医院内分泌科,400016

出　　处：《中华内分泌代谢杂志》2014年第9期760-764,共5页Chinese Journal of Endocrinology and Metabolism

基　　金：国家自然科学基金资助项目（81270911）;中华医学会内分泌学分会研究经费资助

摘　　要：目的 调查重庆市35岁及以上人群代谢综合征（MS）的患病率及其分布特征.方法 采用分层整群随机抽样的调查方法,在重庆市35岁及以上人群中进行横断面调查,获得有效调查人数为5 384人,检测该人群的空腹血糖、血脂、身高、体重、腰臀围、血压等,并行口服葡萄糖耐量试验,运用国际糖尿病联盟（IDF,2005）的MS标准对资料进行分析.结果 （1）重庆市MS的粗患病率20.28％,标化患病率为18.72％,女性显著高于男性（25.55％对12.90％,P＜0.01）;（2）城市MS患病率显著高于农村（26.65％对16.94％,P＜0.01）;（3） MS患病率随年龄的增长而增加,65岁以上年龄组患病率最高;（4）MS的各组分中,中心性肥胖、高甘油三酯血症、高血糖、高血压、低高密度脂蛋白胆固醇的患病率分别为30.11％、26.17％、43.93％、54.03％和27.23％.人群中至少有1种以上组分异常的个体高达83.06％,同时合并4项危险因素的组合形式以“中心性肥胖＋高甘油三酯血症＋高血糖＋高血压”为最多.结论 重庆市35岁以上人群MS患病率较高,MS已越来越成为影响重庆城乡居民健康和生命的重大公共卫生问题,亟需对MS做出早期诊断并加强综合防治.Objective To investigate the prevalence and epidemiologic characteristics of metabolic syndrome （MS） in adults aged over 35 years in Chongqing.Methods Randomly selected adults were studied by means of multi-stage sampling.A cross-sectional study was conducted in Chongqing with a representative sample of 5 384 Chinese adults aged over 35 years.After an overnight fasting,participants underwent an oral glucose tolerance test,fasting and 2-hour plasma glucose,blood lipid profile as well as height,body weight,blood pressure were measured.In this survey,the prevalence of MS was analyzed according to the diagnostic criteria of International Diabetes Federation in 2005.Results The crude prevalence of MS was 20.28％,and the standardized prevalence was 18.72％ after age was adjusted.Compared to male population,female participants showed a higher prevalence （25.55％ vs 12.90％,P＜0.01）.The prevalence of MS was higher in urban residents than in rural （26.65％ vs 16.94％,P＜0.01）.The prevalence of MS increased with age,along with the highest prevalence in the group aged over 65 years.The incidences of central obesity,high triglyceridemia,hyperglycemia,hypertension,and low highdensity lipoprotein-cholesterol were 30.11％,26.17％,43.93％,54.03％,and 27.23％,respectively.There were at least 83.06％ subjects who possessed more than 1 risk factor.The most common combination of four components of MS were central obesity,high triglyceridemia,hyperglycemia,and hypertension.Conclusion There is a high prevalence of MS in adult residents in Chongqing.MS is increasingly becoming a noteworthy health problem requiring urgent attention for its prevention and treatment.

关 键 词：代谢综合征 患病率 流行病学 

分 类 号：R589[医药卫生—内分泌]