鞍山地区慢性腹泻患者食物不耐受情况的初步调查  

A preliminary survey of food intolerance in patient with chronic diarrhea within Anshan area

作　　者：迟鹏[1] 葛丽辉[1] 

机构地区：[1]辽宁省鞍山市中心医院消化科,辽宁鞍山114001

出　　处：《中国医药科学》2014年第18期156-158,共3页China Medicine And Pharmacy

摘　　要：目的探讨鞍山地区食物不耐受与慢性腹泻发病的相关性。方法采用ELISA半定量法检测102例慢性腹泻患者血清中14种食物的水平。结果慢性腹泻患者所测食物中以蟹的IsG抗体阳性率(48.0%)最高,其次为虾(41.2%)、蛋清/蛋黄(36.3%)和牛奶(23.5%),再次为鳕鱼(19.6%)和小麦(16.7%);慢性腹泻患者食物特异性IgG抗体检测的总阳性率为88.2%(90/102),其中1种食物IgG抗体阳性率为30.4%(31/102),2种以上者为57.8%(59/102)。结论食物不耐受是本地区慢性腹泻的致病因素之一,检测食物特异性IsG抗体对于了解慢性腹泻的发病机制和指导临床治疗具有积极的意义。Objective To explore the correlation between food intolerance and chronic diarrhea within Anshan area. Methods The food intolerance specific IgG antibodies in serum were measured by enzyme-1inked immunosorbent assay（ELISA） in 102 patients with chronic diarrhea.Results The most common elevated food intolerance specific IgG detected was the one against crab（48.0%）,followed by shrimp（41.2%）,egg（36.3%%）,milk（23.2%）,cod（19.6%） and wheat（16.7%）.The total positive rate of the test was 88.2%（90/102）,and 30.4%（31/102）of the patients showed elevated levels of one type of antibodies and 57.8%（59/102）of the patients showed at least 2 types of antibodies. Conclusion Food intolerance is an important etiological factor.Detection of specific IgG antibodies of food intolerance is significant for understanding pathogenesy of chronic diarrhea and direct clinical treatment.

关 键 词：慢性腹泻 食物不耐受 特异性IGG抗体 

分 类 号：R758.2[医药卫生—皮肤病学与性病学]