新生儿溶血病换血疗法几种血液配型方案的疗效评价  

Evaluate of therapeutic effect of different blood compatibility program in exchange transfusion for hemolytic disease of the newborn

作　　者：马红丽[1] 刘瑞玲[1] 孙雪梅[1] 

机构地区：[1]洛阳市中心血站输血研究所,河南洛阳471000

出　　处：《中国输血杂志》2014年第9期954-956,共3页Chinese Journal of Blood Transfusion

摘　　要：目的探讨新生儿溶血病换血疗法几种血液配型方案的疗效评价,选取适宜的血液配型方案,提高新生儿溶血病换血治疗效果。方法对2009～2013年68例新生儿溶血病换血治疗,根据不同种类病因,选取适宜的血液配型方案,比较治疗前后Hb、血清胆红素及血液生化指标变化。结果适宜的血液配型方案使68名患儿换血治疗后血清总胆红素、直接胆红素、间接胆红素分别下降64.90%、44.37%、62.61%;Hb数值换血后与换血前比较P〈0.01;血糖检测换血后与换血前比较P〈0.01,其他生化指标检测换血后与同组换血前比较P〉0.05。结论新生儿溶血病换血疗法,根据不同血型系统选取适宜的血液配型方案,能快速缓解患儿症状,提高治疗效果,对提倡优生优育政策及构建和谐社会具有重要的现实意义。Objective To evaluate the therapeutic effect of several compatibility principles of exchange transfusion for neonatal hemolysis disease. To choose a suitable program for improving the effect of changing blood. Methods 68 cases with neonatal hemolysis disease received exehang transfusion from 2009 to 2013. Appropriate blood compatibility program was selected according to different causes of disease. The level of hemoglobin, serum bilirubin and blood biochemical indicators were compared before and after exchange transfusion. Results The total serum bilirubin, direct bilirubin, indirect bilirubin de0. 01 ） after transfusion. Other biochemical indicators didn＇t show significant changes（ P 〉 0. 05 ）. Conclusion Selecting the suitable blood compatibility program according to different blood type can quickly alleviate symptoms and improve the effect of the treatment,which have important practical significance in advocatting eugenics policy and building a harmonious society.

关 键 词：新生儿溶血病 换血疗法 疗效评价 

分 类 号：R457.11[医药卫生—治疗学] R722.18[医药卫生—临床医学]