三维斑点追踪技术评价阻塞性睡眠呼吸暂停综合征患者左心室收缩功能  被引量:4

Three-dimensional speckle-tracking echocardiography assesses left ventricular systolic function in patients with obstructive sleep apnea

在线阅读下载全文

作  者:周年伟 李政[1] 沈洪[2] 李善群[3] 舒先红[1] 巩雪[1] 陈海燕[1] 赵维鹏[1] 潘翠珍[1] 

机构地区:[1]上海市影像医学研究所 复旦大学附属中山医院 上海市心血管病研究所超声心动图室,200032 [2]复旦大学附属中山医院急诊科 [3]复旦大学附属中山医院呼吸科

出  处:《中华临床医师杂志(电子版)》2014年第17期6-9,共4页Chinese Journal of Clinicians(Electronic Edition)

基  金:国家自然科学基金(81371576)

摘  要:目的应用三维斑点追踪技术评价阻塞性睡眠呼吸暂停综合征(OSA)患者左心室收缩功能。方法应用三维斑点追踪技术对经昼夜多导睡眠监测仪确诊的OSA患者[根据睡眠呼吸暂停指数(AHI)>5次/h]39例和所有检测指标正常的正常对照组45例进行左心室心肌斑点追踪分析,比较两组的BMI、左心室射血分数(LVEF)及左心室三维应变指标,并且分析比较AHI、BMI与三维应变指标之间的相关性。结果 (1)与正常人比较,OSA患者的BMI、左心室舒张末期容积(EDV)、左心室收缩末期容积(ESV)均明显增大(P<0.05);OSA患者左心室三维环向、径向应变值较正常人有明显减小(P<0.05);(2)相关性分析:BMI与EDV、ESV、长轴应变、径向应变、扭转、扭转度有较好的相关性:EDV(r=0.523,P<0.01),ESV(r=0.617,P<0.01),长轴(r=-0.402,P<0.01),环向(r=-0.284,P>0.05),径向应变(r=-0.423,P<0.01),扭转(r=-0.370,P<0.05),扭矩(r=-0.419,P<0.01)。结论三维应变参数能够敏感反映OSA患者左心功能改变,其中三维环向及径向应变能够在患者LVEF发生改变之前反映心功能的变化且左心功能的改变与BMI有关。Objective To evaluate left ventricular (LV) function in patients with obstructive sleep apnea(OSA) compared with controls without OSA using three-dimensional speckle-tracking echocardiography.Methods Thirty-nine patients with mild to severe OSA and forty-five controls were in this study whose apnea hypopnea index (AHI), body mass index (BMI), left ventricular ejection fraction (LVEF) and left ventricular three-dimensional index were analyzed. All subjects underwent polysomnography and three-dimensional echocardiography.Results OSA patients had a larger BMI, left ventricular end diastolic volume (EDV), left ventricular end systolic volume (ESV) and smaller left ventricular three-dimensional circumferential strain, radial strain than control group (P〈0.01 for all); BMI and EDV (r=0.523,P〈0.01), ESV (r=0.617,P〈0.001), longitudinal strain (r=-0.402,P〈0.01), radial strain (r=-0.423,P〈0.01), twist (r=-0.370,P〈0.05), torsion (r=-0.419,P〈0.01) had good correlation. Conclusions Three-dimensional strain parameter is sensitive to reflect the changes of left heart function in patients with OSA. The circumferential strain and radial strain can reflect the changes of cardiac function before the change of LVEF in the patients and left ventricular function changes associated with BMI.

关 键 词:睡眠呼吸暂停 阻塞性 三维斑点追踪 应变 

分 类 号:R766[医药卫生—耳鼻咽喉科] R540.45[医药卫生—临床医学]

 

参考文献:

正在载入数据...

 

二级参考文献:

正在载入数据...

 

耦合文献:

正在载入数据...

 

引证文献:

正在载入数据...

 

二级引证文献:

正在载入数据...

 

同被引文献:

正在载入数据...

 

相关期刊文献:

正在载入数据...

相关的主题
相关的作者对象
相关的机构对象