光纤SPR传感器在抗感染中药作用机理的应用  

Application of optical fiber SPR sensor in anti infection mechanism of traditional Chinese medicine

作　　者：张鹤林[1] 张康[1] 张国龙[1] 陈庆梅[1] 

机构地区：[1]江西中医药大学计算机学院,江西南昌330004

出　　处：《传感器与微系统》2014年第10期155-156,160,共3页Transducer and Microsystem Technologies

基　　金：江西省卫生厅中医药科研项目(2013A088);江西中医药大学重点学科资助项目(2013JZZDXK032)

摘　　要：提出一种基于光纤表面等离子体共振(SPR)传感器的检测法,检测抗感染中药与细胞因子和受体间的相互作用。采用真空热蒸镀法镀双层金属膜制作一种双金属光纤SPR生物传感器,应用直接法完成中药作用机理检测。该传感器具有快速、客观、准确、高效的中药作用机理检测功能,获得了相应数据。光纤SPR生物传感器的应用使得中药作用机理过程的检测具有实时高效的优点,有望在抗感染中药作用的靶点和分子机理研究中取得新的突破。Put forward a detection method based on optical fiber SPR sensor, detect interaction of anti infection traditional Chinese medicine and cytokines and receptors. Vacuum thermal evaporation method is used to plate double layer metal film to fabricate a kind of double metal fiber SPR biosensor, direct method is applied to complete mechanism detection of traditional Chinese medicine. The sensor has working mechanism detection function of traditional Chinese medicine of fast, objective, accurate, and high efficient and corresponding datas are obtained. Application of fiber-optic SPR biosensor makes process detection of working mechanism of traditional Chinese medicine has advantages of high efficient and real time, it is expected to achieve new breakthroughs in target point of anti infection traditional Chinese medicine and molecular mechanism research.

关 键 词：表面等离子体共振传感器 中药 作用机理 

分 类 号：TP212.3[自动化与计算机技术—检测技术与自动化装置]