多层螺旋CT联合^(99m)Tc-MIBI亲肿瘤显像对孤立性肺结节的诊断价值探讨  

The value of ^(99m)Tc-MIBI tumor imaging combined with multi-slice spiral CT for diagnosis of solitary pulmonary nodule

作　　者：杨文定[1] 韦璐[2] 陈刚[2] 肖运平[2] 覃绍超[1] 

机构地区：[1]广西医科大学附属柳州市人民医院核医学科,广西柳州545006 [2]广西医科大学附属柳州市人民医院放射科,广西柳州545006

出　　处：《现代预防医学》2014年第18期3424-3426,共3页Modern Preventive Medicine

基　　金：广西壮族自治区卫生厅自筹经费科研课题(Z2012572)

摘　　要：目的探讨99mTc-甲氧异丁基异睛(99mTc-MIBI)肺亲肿瘤显像与多层螺旋CT联合诊断孤立性肺结节中的临床价值。方法对50例X线胸片发现孤立性肺结节的患者均进行99mTc-MIBI肺肿瘤显像、多层螺旋CT扫描,将结果与手术及病理结果对照,分别及联合计算两种方法鉴别诊断孤立性肺结节中的灵敏度、特异性、准确性。结果 99mTc-MIBI亲肿瘤显像诊断肺结节的灵敏度、特异性、准确性分别为76.9%,81.8%,78.0%;多层螺旋CT扫描为76.9%,72.7%,76.0%。两种检测方法联合运用为94.9%、90.9%和94.0%。结论 99mTc-MIBI肺部亲肿瘤显像联合多层螺旋CT检测提高了对孤立性肺结节的诊断价值。Objective The purpose of this study was to investigate the clinical value of ^99mTc -MIBI tumor imaging combined with multi-slice spiral CT scan in diagnosing solitary pulmonary nodule （SPN）. Methods Fifty patients with SPN were examined with CT scan and ^99mTc -MIBI tumor imaging. The diagnosis was compared with the results by pathology examination. The diagnostic sensitivity, specificity and accurate of both methodologies were analyzed and compared in combination with calculation for SPN. Results The diagnostic sensitivity, specificity and accurate value in assessing SPN were 76.9%, 81.8%, 78.0% by ^99mTc-MIBI tumor imaging; 76.9%, 72.7%, 76.0% by CT scan; 94.9%, 90.9%, and 94.0% by combining both methodologies. Conclusion The combination of both ^99mTc -MIBI tumor imaging and multi-slice spiral CT scan were helpful in improving the accuracy of the diagnosis for malignant SPN.

关 键 词：肺结节 核医学 体层摄影术 X线计算机 

分 类 号：R319[医药卫生—基础医学] R445