2型糖尿病患者的三维超声胰腺体积测量  

Measurement of pancreatic volume in patients with type 2 diabetes by three-dimensional ultrasound

作　　者：袁南兵[1] 程印蓉[2] 陆志明[1] 戴宗耀[2] 李嘉俊[2] 崔西振[2] 

机构地区：[1]成都市第一人民医院内分泌科,四川成都610016 [2]成都市第一人民医院超声诊断科,四川成都610016

出　　处：《现代预防医学》2014年第18期3427-3429,共3页Modern Preventive Medicine

基　　金：四川省卫生厅科研课题(080060)

摘　　要：目的探讨不同年龄段2型糖尿病患者的胰腺体积变化,为临床2型糖尿病评估提供新的方法。方法纳入41~50岁,51~60岁,61~70岁以及71岁以上2型糖尿病患者各50例,同时按照不同年龄段选择非糖尿病成人各50例,使用三维彩色超声诊断系统进行胰腺体积测量。结果 2型糖尿病患者血糖、血脂均高于非糖尿病人群,2型糖尿病患者胰腺体积在41~50岁和51~60岁年龄段明显小于非糖尿病人群（P〈0.05）。61岁以后两组没有差别（P〉0.05）。男性胰腺体积明显大于女性（P〈0.05）。结论成人41岁以后胰腺开始逐渐萎缩,至61岁以后达到稳定,2型糖尿病患者的胰腺萎缩较非糖尿病人群提前发生。Objective The objective of the study was to investigate the change in pancreatic volume over age in patients with type 2 diabetes, so to provide a new approach for the assessment of type 2 diabetes. Methods Type 2 diabetic patients aged between 41-50, 51-60, 61-70, and 71 and over, with 50 patients in each age group, were included for the study; 50 non-diabetic adults were also selected for each age group. Pancreatic volume of the subjects was measured by a three-dimensional color ultrasonic diagnostic system. Results Blood glucose and blood lipids of patients with type 2 diabetes were higher than those of the non-diabetic controls. The diabetic patients at the 41-50 and 51-60 age groups had significantly smaller pancreatic volume than the non-diabetic controls （P〈0.05）; however, the subjects older than 61 had no difference in pancreatic volume （P〉0.05）. Pancreatic volume in male was significantly larger than that in female （P〈0.05）. Conclusion Pancreas generally begins to shrink after the age of 41 until 61. Pancreatic atrophy occurs earlier in patients with type 2 diabetes than in non-diabetic individuals.

关 键 词：2型糖尿病 胰腺体积 三维超声 

分 类 号：R319[医药卫生—基础医学] R445.1