芜湖市患儿巨细胞病毒感染回顾性分析  

Retrospective analysis of cytomegalovirus infection in children of Wuhu City

作　　者：苏贵灵[1] 李光友[2] 王佐[1] 潘嘉严 

机构地区：[1]安徽省芜湖市第一人民医院儿科,241000 [2]安徽省芜湖市第二人民医院检验科,241000

出　　处：《国际儿科学杂志》2014年第5期557-558,共2页International Journal of Pediatrics

摘　　要：目的：了解芜湖市患儿巨细胞病毒感染状况。方法应用酶联免疫吸附试验对874例可疑巨细胞病毒感染患儿血清CMV-IgM抗体进行检测。结果874例患儿CMV-IgM检出率为4．46%。其中男童阳性26例（26/531）,阳性率4．89%；女童阳性13例（13/343）,阳性率3．79%；男童与女童CMV-IgM阳性率之间差异无统计学意义（χ2=0．37,P〉0．05）。在不同年龄组中,以〉6个月-1岁组阳性率最高,达10．19%。其中主要表现依次为肝功能异常、神经系统疾病、黄疸、肺炎。结论芜湖市患儿CMV感染率较高,应引起儿科医生的重视。Objective To investigate the cytomegalovirus（ CMV） infection in children of Wuhu City. Methods Serum samples from children n=874 were tested for CMV-IgM using commercial ELISA kits. Re-sults The CMV-IgM detective rate of serum samples from 874 children was 4. 46%. The positive rate of CMV-IgM was 4. 89%（26/531cases）and 3. 79%（13/343 cases）in boys and girls,respectively. There was no signifi-cant difference in the positive rate of CMV-IgM between boys and girls（χ2 =0. 37,P〉0. 05）. The positive rate peaked in children at age of 〉6 months-1 year（10. 19%）. Clinical manifestations included liver dysfunction, neurological diseases,jaundice and pneumonia. Conclusion The positive rate of CMV-IgM in children in local district of Wuhu city is high,which should be given due attention.

关 键 词：巨细胞病毒 感染 患儿 

分 类 号：R725.1[医药卫生—儿科]