改良封闭负压辅助闭合技术在下肢静脉性溃疡的应用  

Application of Vacuum-assisted Closure in the Treatment of Venous Ulcer of Lower Extremities

作　　者：蔡秋妮[1] 卢伟锋[1] 杨东海[1] 黄小进[1] 张素真[1] 陈采茶 

机构地区：[1]厦门大学附属中山医院血管外科,福建厦门361003

出　　处：《华西医学》2014年第9期1603-1606,共4页West China Medical Journal

基　　金：国家自然科学基金青年科学基金(81100225)~~

摘　　要：目的探讨改良封闭负压辅助闭合技术在下肢静脉性溃疡的应用。方法选取2013年1月-2014年1月住院的下肢静脉性溃疡患者37例,其中男21例,女16例,按照随机数字表法分为试验组19例[年龄为(66.47±6.22)岁]和对照组18例[年龄为(66.39±5.37)岁]。试验组用改良封闭负压辅助闭合技术进行伤口处理,对照组用常规湿性疗法换药,观察两组伤口愈合情况以及患者痛觉评分。统计学方法采用χ2检验及t检验。结果试验组创面愈合率为84.2%,对照组创面愈合率为55.6%,两组比较差异无统计学意义(P=0.079)。对照组1例经1个月换药等综合治疗后效果差,自动出院。试验组患者创面愈合时间为(13.84±3.13)d,明显短于对照组[(27.35±1.73)d],两组比较差异有统计学意义(t=-16.360,P<0.001);试验组患者疼痛评分为(3.53±0.51)分,明显低于对照组[(4.41±0.51)分],两组比较差异有统计学意义(t=-5.197,P<0.001)。结论改良封闭负压辅助闭合技术对下肢静脉性溃疡的愈合有明显的促进作用,并能减轻下肢静脉性溃疡患者的伤口疼痛。Objective To analyze the clinical effect of vacuum-assisted closure in treating venous ulcer. Methods Thirty seven patients including 21 males and 16 females with lower extremity venous ulcer treated in our hospital from January 2013 to January 2014 were included in our study. Based on random number table, the patients were divided into treatment group [n=19, （66.47± 6.22） years old] and control group [n=18, （66.39± 5.37） years old]. The treatment group received vacuum-assisted closure, while the control group underwent routine moist therapy. Wound healing and visual analogue pain scores were observed. Chi-square test and t-test were used for statistical analysis. Results Wound healing rate was 84.2% in the treatment group and 55.6% in the control group, and the difference between the two groups was statistically significant （X2= 26.66, P 〈 0.05）. Wound healing time was （13.84±3.13） days in the treatment group and （27.35 ± 1.73） days in the control group, and the difference was statistically significant （t=-7.498, P 〈 0.01）. Visual analogue pain scores in the treatment group was 3.53 ± 0.51, and in the control group, it was 4.41 ± 0.51, and the difference was statistically significant （t=-5.197, P 〈 0.01）. Condusion Vacuum-assisted closure can significantly improve wound healing and alleviate sufferings in the treatment of venous ulcer.

关 键 词：封闭负压辅助闭合技术 静脉性溃疡 愈合 

分 类 号：R472[医药卫生—护理学]