高血压晨峰现象与动态动脉硬化指数相关性研究  

Correlation between Morning Blood Pressure Surge and Ambulatory Arterial Stiffness Index

作　　者：李俊峰[1] 王安伟[1] 高金全[1] 陈晓平[2] 张亚西[1] 张红[1] 刘瑶[1] 

机构地区：[1]崇州市人民医院心血管内科,四川崇州611330 [2]四川大学华西医院心脏内科

出　　处：《华西医学》2014年第9期1639-1641,共3页West China Medical Journal

基　　金：四川省卫生厅科研课题(120459)~~

摘　　要：目的观察高血压晨峰现象与动态动脉硬化指数(AASI)的相关性,了解高血压晨峰现象在评估动脉硬化方面的价值。方法 2011年5月-2013年3月,选取300例原发性高血压患者,完善动态血压检查后分为晨峰高血压组及非晨峰组,并依据患者血压分级进一步分为3个亚组,记录AASI值,对比晨峰高血压患者和非晨峰患者AASI的差异。结果晨峰组患者AASI明显高于非晨峰组患者,差异有统计学意义(P<0.05)。亚组分析显示,高血压1级患者晨峰组与非晨峰组ASSI差异无统计学意义(P>0.05);高血压2级患者晨峰组AASI高于非晨峰组(P<0.05);高血压3级患者晨峰组AASI高于非晨峰组(P<0.05)。结论晨峰现象与动脉硬化之间存在一定关联,可能是导致各种靶器官损伤的重要原因。Objective To investigate the value of morning blood pressure surge in the evaluation of atherosclerosis by the observation of the relationship between morning blood pressure surge and ambulatory arterial stiffness index. Methods From May 2011 to March 2013, we followed up 300 hypertensive patients who received ambulatory blood pressure monitoring, and they were divide into elevated morning blood pressure surge group and non-elevated morning blood pressure surge group. The AASI value was recorded and compared between the two groups according to the grade of hypertension. Results Morning blood pressure surge was more common in patients with hypertension. Compared with patients in the non-elevated morning blood pressure surge group, ambulatory arterial stiffness index was significantly higher in patients in the elevated morning blood pressure surge group. Conclusion There is a certain correlation between morning blood pressure surge and arterial stiffness, which is an important factor leading to a variety of target organ damage.

关 键 词：原发性高血压 晨峰高血压现象 动态血压监测 动脉硬化 

分 类 号：R544.1[医药卫生—心血管疾病]